Mechanisms and treatment of organ failure in sepsis
C Lelubre, JL Vincent - Nature Reviews Nephrology, 2018 - nature.com
Sepsis is a dysregulated immune response to an infection that leads to organ dysfunction.
Knowledge of the pathophysiology of organ failure in sepsis is crucial for optimizing the …
Knowledge of the pathophysiology of organ failure in sepsis is crucial for optimizing the …
Critical care hepatology: definitions, incidence, prognosis and role of liver failure in critically ill patients
A Perez Ruiz de Garibay, A Kortgen, J Leonhardt… - Critical Care, 2022 - Springer
Organ dysfunction or overt failure is a commonplace event in the critically ill affecting up to
70% of patients during their stay in the ICU. The outcome depends on the resolution of …
70% of patients during their stay in the ICU. The outcome depends on the resolution of …
Characteristics, outcomes, and trends of patients with COVID-19–related critical illness at a learning health system in the United States
Background: The coronavirus disease 2019 (COVID-19) pandemic continues to surge in the
United States and globally. Objective: To describe the epidemiology of COVID-19–related …
United States and globally. Objective: To describe the epidemiology of COVID-19–related …
Machine learning for real-time prediction of complications in critical care: a retrospective study
A Meyer, D Zverinski, B Pfahringer… - The Lancet …, 2018 - thelancet.com
Background The large amount of clinical signals in intensive care units can easily
overwhelm health-care personnel and can lead to treatment delays, suboptimal care, or …
overwhelm health-care personnel and can lead to treatment delays, suboptimal care, or …
Higher fluid balance increases the risk of death from sepsis: results from a large international audit
Objectives: Excessive fluid therapy in patients with sepsis may be associated with risks that
outweigh any benefit. We investigated the possible influence of early fluid balance on …
outweigh any benefit. We investigated the possible influence of early fluid balance on …
Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis
AA Fowler, AA Syed, S Knowlson, R Sculthorpe… - Journal of translational …, 2014 - Springer
Background Parenterally administered ascorbic acid modulates sepsis-induced
inflammation and coagulation in experimental animal models. The objective of this …
inflammation and coagulation in experimental animal models. The objective of this …
Acute noncardiac organ failure in acute myocardial infarction with cardiogenic shock
S Vallabhajosyula, SM Dunlay, A Prasad… - Journal of the American …, 2019 - jacc.org
Background: There are limited data on acute noncardiac multiorgan failure in cardiogenic
shock complicating acute myocardial infarction (AMI-CS). Objectives: The authors sought to …
shock complicating acute myocardial infarction (AMI-CS). Objectives: The authors sought to …
Improving detection of patient deterioration in the general hospital ward environment
Patient monitoring on low acuity general hospital wards is currently based largely on
intermittent observations and measurements of simple variables, such as blood pressure …
intermittent observations and measurements of simple variables, such as blood pressure …
Multiple organ dysfunction after trauma
Background The nature of multiple organ dysfunction syndrome (MODS) after traumatic
injury is evolving as resuscitation practices advance and more patients survive their injuries …
injury is evolving as resuscitation practices advance and more patients survive their injuries …
Acute respiratory failure and mechanical ventilation in cardiogenic shock complicating acute myocardial infarction in the USA, 2000–2014
S Vallabhajosyula, K Kashani, SM Dunlay… - Annals of intensive …, 2019 - Springer
Background There are limited epidemiological data on acute respiratory failure (ARF) in
cardiogenic shock complicating acute myocardial infarction (AMI-CS). This study sought to …
cardiogenic shock complicating acute myocardial infarction (AMI-CS). This study sought to …