▪ Abstract Phenotypic variation for quantitative traits results from the segregation of alleles at
multiple quantitative trait loci (QTL) with effects that are sensitive to the genetic, sexual, and …

Although many studies have examined quantitative trait variation across many species, only
a small number of genes and thereby molecular mechanisms have been discovered …

Aging or senescence is an age-dependent decline in physiological function,
demographically manifest as decreased survival and fecundity with increasing age. Since …

The genetic variants underlying complex traits are often elusive even in powerful model
organisms such as Caenorhabditis elegans with controlled genetic backgrounds and …

Congenic lines that differ in a single defined chromosome segment are useful for the study
of complex phenotypes, as they allow isolation of the effect of a particular quantitative trait …

The ability to withstand periods of scarce food resources is an important fitness trait.
Starvation resistance is a quantitative trait controlled by multiple interacting genes and …

Recombinant inbred lines (RILs) derived from Caenorhabditis elegans wild-type N2 and
CB4856 are increasingly being used for mapping genes underlying complex traits. To speed …

Increased lifespan can be associated with greater resistance to many different stressors,
most notably thermal stress. Such hormetic effects have also been found in C. elegans …

Caenorhabditis elegans expresses a glutathione transferase (GST) belonging to the Pi
class, for which we propose the name CeGSTP2‐2. CeGSTP2‐2 (the product of the gst‐10 …

Research into the genetic and environmental factors behind complex trait variation has
traditionally been segregated into distinct scientific camps. The reductionist approach aims …