Background Mitochondrial dysfunction may contribute to brain and muscle health through
inflammation or fat infiltration in the muscle, both of which are associated with cognitive …

Abstract The HEALthy Brain and Child Development (HBCD) Study, a multi-site prospective
longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and …

The mitochondrial cascade hypothesis of Alzheimer's disease (AD) has been portrayed
through molecular, cellular, and animal studies; however large epidemiological studies are …

Background Mitochondrial dysfunction (MD) is increasingly recognized as a key
pathophysiological contributor in Alzheimer disease (AD). As differential MD genes …

Background Lower skeletal muscle mitochondrial function is associated with future cognitive
impairment and mobility decline, but the biological underpinnings for these associations are …

Mitochondrial dysfunction is linked to physical impairment and dementia. Mitochondrial DNA
copy number (mtDNAcn) from blood may predict cognitive decline and dementia risk, but the …

Background. Inconsistent findings characterize studies on mitochondrial DNA copy number
(mtDNA-CN) and its relation to neuropsychiatric disorders. This bidirectional two-sample …

Beyond the relationship between mitochondria and mobility in aging - PMC Back to Top Skip to
main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content …

Exposure to stressful situations occurs throughout an organism's life. Stress can be defined
as events that threaten an individual, triggering physiological and behavioral responses as …

Mitochondria are responsible for several crucial cellular processes and contain their own
DNA (mtDNA) that exists in several copies. Variation of mtDNA copy number (mtDNA-CN) …