The term differences of sex development (DSDs; also known as disorders of sex
development) refers to a heterogeneous group of congenital conditions affecting human sex …

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About 10% of women of reproductive age are unable to conceive or carry a pregnancy to
term. Female factors alone account for at least 35% of all infertility cases and comprise a …

Highlights•Sex development depends on spatio-temporal sequence & coordination of
mutually antagonistic activating & repressing factors.•Disorders of sex development can be …

Despite being collectively among the most frequent congenital developmental conditions
worldwide, differences of sex development (DSD) lack recognition and research funding. As …

The medical term disorders of sex development (DSDs) is used to describe individuals with
an atypical composition of chromosomal, gonadal and phenotypic sex, which leads to …

Sex development relies on the sex-specific action of gene networks to differentiate the
bipotential gonads of the growing fetus into testis or ovaries, followed by the differentiation of …

A woman's reproductive health and ability to have children directly affect numerous aspects
of her life, from personal well-being and socioeconomic standing, to morbidity and lifespan …

Purpose We aimed to identify the genetic cause in a cohort of 11 unrelated cases and two
sisters with 46, XX SRY-negative (ovo) testicular disorders of sex development (DSD) …

Context: The prevalence of phenotypic females with a 46, XY karyotype is low, thus current
knowledge about age and clinical presentation at diagnosis is sparse even for the most …