DNA nanotechnology

NC Seeman, HF Sleiman - Nature Reviews Materials, 2017 - nature.com
DNA is the molecule that stores and transmits genetic information in biological systems. The
field of DNA nanotechnology takes this molecule out of its biological context and uses its …

DNA as a versatile chemical component for catalysis, encoding, and stereocontrol

SK Silverman - Angewandte Chemie International Edition, 2010 - Wiley Online Library
DNA (deoxyribonucleic acid) is the genetic material common to all of Earth's organisms. Our
biological understanding of DNA is extensive and well‐exploited. In recent years, chemists …

Self‐Assembled Multivalency: Dynamic Ligand Arrays for High‐Affinity Binding

A Barnard, DK Smith - Angewandte Chemie International …, 2012 - Wiley Online Library
Multivalency is a powerful strategy for achieving high‐affinity molecular recognition in
biological systems. Recently, attention has begun to focus on using self‐assembly rather …

Terminal protection of small-molecule-linked DNA for sensitive electrochemical detection of protein binding via selective carbon nanotube assembly

Z Wu, Z Zhen, JH Jiang, GL Shen… - Journal of the American …, 2009 - ACS Publications
Small-molecule-linked DNA has emerged as a versatile tool for the interaction assay
between small organic molecules and their protein receptors. We report herein the proof-of …

Liberation of copper from amyloid plaques: making a risk factor useful for Alzheimer's disease treatment

J Geng, M Li, L Wu, J Ren, X Qu - Journal of medicinal chemistry, 2012 - ACS Publications
Alzheimer's disease (AD) is a complex multifactorial syndrome. Metal chelator and Aβ
inhibitor are showing promise against AD. In this report, three small hybrid compounds (1, 2 …

The Creation of DNA Origami‐Based Supramolecular Nanostructures for Cancer Therapy

S Zhang, XY Lou, L Liu, YW Yang - Advanced Healthcare …, 2023 - Wiley Online Library
DNA origami technology, a unique type of DNA nanotechnology, has attracted much
attention from researchers and is applied in various fields. Through exquisite design and …

Decorating bacteria with self-assembled synthetic receptors

N Lahav-Mankovski, PK Prasad… - Nature …, 2020 - nature.com
The responses of cells to their surroundings are mediated by the binding of cell surface
proteins (CSPs) to extracellular signals. Such processes are regulated via dynamic changes …

Targeted protein surface sensors as a tool for analyzing small populations of proteins in biological mixtures

L Motiei, Z Pode, A Koganitsky… - Angewandte …, 2014 - Wiley Online Library
Optical cross‐reactive sensor arrays (the so‐called chemical “noses/tongues”) have recently
been demonstrated as a powerful tool for high‐throughput protein detecting and analysis …

Ultratrace detection of C-reactive protein by a piezoelectric immunosensor based on Fe3O4@ SiO2 magnetic capture nanoprobes and HRP-antibody co-immobilized …

J Zhou, N Gan, T Li, H Zhou, X Li, Y Cao… - Sensors and Actuators B …, 2013 - Elsevier
An ultra-sensitive multiplexed signal amplified piezoelectric immunosensor for the detection
of C-reactive protein (CRP) in serum was developed. Firstly, a sandwich-type …

Recent advances in DNA-encoded dynamic libraries

B Shi, Y Zhou, X Li - RSC Chemical Biology, 2022 - pubs.rsc.org
The DNA-encoded chemical library (DEL) has emerged as a powerful technology platform in
drug discovery and is also gaining momentum in academic research. The rapid …