A detailed landscape of CRISPR-Cas-mediated plant disease and pest management
Genome editing technology has rapidly evolved to knock-out genes, create targeted genetic
variation, install precise insertion/deletion and single nucleotide changes, and perform large …
variation, install precise insertion/deletion and single nucleotide changes, and perform large …
Cell-derived extracellular vesicles for CRISPR/Cas9 delivery: engineering strategies for cargo packaging and loading
Y Liang, Z Iqbal, J Wang, L Xu, X Xu, K Ouyang… - Biomaterials …, 2022 - pubs.rsc.org
Genome editing technology has emerged as a potential therapeutic tool for treating
incurable diseases. In particular, the discovery of clustered regularly interspaced short …
incurable diseases. In particular, the discovery of clustered regularly interspaced short …
[HTML][HTML] Rapid and accurate nucleobase detection using FnCas9 and its application in COVID-19 diagnosis
Rapid detection of DNA/RNA pathogenic sequences or variants through point-of-care
diagnostics is valuable for accelerated clinical prognosis, as witnessed during the recent …
diagnostics is valuable for accelerated clinical prognosis, as witnessed during the recent …
The tracrRNA in CRISPR biology and technologies
CRISPR-Cas adaptive immune systems in bacteria and archaea utilize short CRISPR RNAs
(crRNAs) to guide sequence-specific recognition and clearance of foreign genetic material …
(crRNAs) to guide sequence-specific recognition and clearance of foreign genetic material …
CRISPR-based tools: Alternative methods for the diagnosis of COVID-19
The recently emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
spread all over the world rapidly and caused a global pandemic. To prevent the virus from …
spread all over the world rapidly and caused a global pandemic. To prevent the virus from …
CRISPR/Cas9 genome editing for tissue‐specific in vivo targeting: nanomaterials and translational perspective
Clustered randomly interspaced short palindromic repeats (CRISPRs) and its associated
endonuclease protein, ie, Cas9, have been discovered as an immune system in bacteria …
endonuclease protein, ie, Cas9, have been discovered as an immune system in bacteria …
An overview of genome engineering in plants, including its scope, technologies, progress and grand challenges
Genome editing is a useful, adaptable, and favored technique for both functional genomics
and crop enhancement. Over the years, rapidly evolving genome editing technologies …
and crop enhancement. Over the years, rapidly evolving genome editing technologies …
CRISPR/Cas-based modifications for therapeutic applications: a review
N Bharathkumar, A Sunil, P Meera, S Aksah… - Molecular …, 2022 - Springer
The CRISPR–Cas genome editing system is an intrinsic property of a bacteria-based
immune system. This employs a guide RNA to detect and cleave the PAM-associated target …
immune system. This employs a guide RNA to detect and cleave the PAM-associated target …
FnCas9-based CRISPR diagnostic for rapid and accurate detection of major SARS-CoV-2 variants on a paper strip
The COVID-19 pandemic originating in the Wuhan province of China in late 2019 has
impacted global health, causing increased mortality among elderly patients and individuals …
impacted global health, causing increased mortality among elderly patients and individuals …
Opportunities and challenges with CRISPR-Cas mediated homologous recombination based precise editing in plants and animals
Key message We summarise recent advancements to achieve higher homologous
recombination based gene targeting efficiency in different animals and plants. Abstract The …
recombination based gene targeting efficiency in different animals and plants. Abstract The …