Challenges and future trends in the treatment of psoriasis

HJ Lee, M Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Psoriasis is a chronic inflammatory skin disorder, and current treatments include topical
therapies, phototherapy, systemic immune modulators, and biologics, aiming to alleviate …

Gold nanoparticles for skin drug delivery

Y Chen, X Feng - International Journal of Pharmaceutics, 2022 - Elsevier
Nanoparticle-based drug carriers are being pursued intensely to overcome the skin barrier
and improve even hydrophilic or macromolecular drug delivery into or across the skin …

The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

J Liu, Z Liu, Y Pang, H Zhou - Journal of Nanobiotechnology, 2022 - Springer
Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of
different materials and adjustment of their physical and chemical properties, nanoparticles …

Mechanisms regulating neutrophil responses in immunity, allergy, and autoimmunity

A Özcan, O Boyman - Allergy, 2022 - Wiley Online Library
Neutrophil granulocytes, or neutrophils, are the most abundant circulating leukocytes in
humans and indispensable for antimicrobial immunity, as exemplified in patients with inborn …

Green synthesis of gold nanoparticles for immune response regulation: Mechanisms, applications, and perspectives

F Cai, S Li, H Huang, J Iqbal, C Wang… - Journal of Biomedical …, 2022 - Wiley Online Library
Immune responses are involved in the pathogenesis of many diseases, including cancer,
autoimmune diseases, and chronic inflammation. These responses are attributed to immune …

[HTML][HTML] Dihydroartemisinin ameliorates psoriatic skin inflammation and its relapse by diminishing CD8+ T-cell memory in wild-type and humanized mice

Y Chen, Y Yan, H Liu, F Qiu, CL Liang, Q Zhang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Conventional immunosuppressants cause side effects and do not prevent the recurrence of
autoimmune diseases. Moreover, they may not inhibit autoimmunity mediated by pathogenic …

Chitosan/hyaluronan nanogels co-delivering methotrexate and 5-aminolevulinic acid: A combined chemo-photodynamic therapy for psoriasis

Y Wang, S Fu, Y Lu, R Lai, Z Liu, W Luo, Y Xu - Carbohydrate Polymers, 2022 - Elsevier
Psoriasis does not respond adequately to the monotherapy, tailoring combined strategies for
synergistical treatment remains challenging. We fabricated chitosan/hyaluronan nanogels to …

A multifunctional composite hydrogel as an intrinsic and extrinsic coregulator for enhanced therapeutic efficacy for psoriasis

J Xu, H Chen, Z Chu, Z Li, B Chen, J Sun, W Lai… - Journal of …, 2022 - Springer
Background Psoriasis is a chronic relapsing immunological skin disease characterized by
multiple cross-talk inflammatory circuits which are relevantly associated with abnormal cross …

[HTML][HTML] Self-therapeutic metal-based nanoparticles for treating inflammatory diseases

R Han, Y Xiao, Q Bai, CHJ Choi - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Inflammatory diseases are key contributors to high mortality globally and adversely affect the
quality of life. Current treatments include corticosteroids or nonsteroidal anti-inflammatories …

Self-assembled nanoparticles with bilirubin/JPH203 alleviate imiquimod-induced psoriasis by reducing oxidative stress and suppressing Th17 expansion

X Jiang, Q Yao, X Xia, Y Tang, M Sun, Y Li… - Chemical Engineering …, 2022 - Elsevier
Psoriasis is a chronic inflammatory skin disease with dysregulation of the immune system,
which usually manifests as erythematous scleroma with hyperplasia of the epidermis …