AASLD Practice Guideline on imaging-based noninvasive liver disease assessment of hepatic fibrosis and steatosis

RK Sterling, A Duarte-Rojo, K Patel, SK Asrani… - Hepatology, 2025 - journals.lww.com
Chronic liver disease (CLD) is associated with approximately two million annual deaths
worldwide and is an enormous health burden.[1, 2] The majority of liver-related outcomes …

Noninvasive liver disease assessment to identify portal hypertension: Systematic and narrative reviews supporting the AASLD Practice Guideline

DC Rockey, M Alsawas, A Duarte-Rojo, K Patel… - Hepatology, 2024 - journals.lww.com
Conclusions: While imaging-based noninvasive liver disease assessment appeared to have
higher accuracy than blood-based tests to detect CSPH, only 9 studies fit the a priori …

AASLD Practice Guideline on noninvasive liver disease assessment of portal hypertension

RK Sterling, SK Asrani, D Levine, A Duarte-Rojo… - Hepatology, 2024 - journals.lww.com
Abbreviations: ALD, alcohol-associated liver disease; APRI, aspartate aminotransferase–
platelet ratio index; ARFI, acoustic radiation force impulse; AUROC, area under the receiver …

The role of noninvasive biomarkers for monitoring cell injury in advanced liver fibrosis

R Riccardo, F Cinque, K Patel… - Expert Review of …, 2025 - Taylor & Francis
Introduction Accurate and reliable diagnosis and monitoring of hepatic fibrosis is
increasingly important given the variable natural history in chronic liver disease (CLD) and …

Fetuin-A: a relevant novel serum biomarker for non-invasive diagnosis of metabolic dysfunction-associated steatotic liver disease (MASLD): a retrospective case …

MM Elhoseeny, BA Abdulaziz, MA Mohamed… - BMC …, 2024 - Springer
Objectives To determine how fetuin-A contributes to diagnosing and assessing MASLD
severity. Methods Fifty MASLD patients and fifty healthy control participants were involved in …

Accurate non-invasive detection of MASH with fibrosis F2-F3 using a lightweight machine learning model with minimal clinical and metabolomic variables

K Stefanakis, G Mingrone, J George, CS Mantzoros - Metabolism, 2025 - Elsevier
Background There are no known non-invasive tests (NITs) designed for accurately detecting
metabolic dysfunction-associated steatohepatitis (MASH) with liver fibrosis stages F2-F3 …

[HTML][HTML] Development of fully automated models for staging liver fibrosis using non-contrast MRI and artificial intelligence: a retrospective multicenter study

C Li, Y Wang, R Bai, Z Zhao, W Li, Q Zhang… - …, 2024 - thelancet.com
Background Accurate staging of liver fibrosis (LF) is essential for clinical management in
chronic liver disease. While non-contrast MRI (NC-MRI) yields valuable information for liver …

Metabolic dysfunction-associated steatotic liver disease: Recent turning points for its diagnosis and management

SA Polyzos, CS Mantzoros - Metabolism-Clinical and …, 2024 - metabolismjournal.com
In the meantime, while endorsing the definition and the criteria of MASLD, during the period
of transition from NAFLD to MASLD, researchers should not uncritically translate NAFLD to …

Platelet‐derived apoptotic vesicles ameliorate nonalcoholic fatty liver disease by regulating lipid metabolism via apolipoprotein A‐II

Y Jiang, Y Liao, Z Wang, L Zhu, Y Liu… - Interdisciplinary …, 2025 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) encompasses a broad range of conditions,
commencing with simple steatosis and progressing to non‐alcoholic steatohepatitis, with the …

[HTML][HTML] Hepatitis B virus infection and its treatment in Eastern Ethiopia

T Kanda, R Sasaki-Tanaka… - World Journal of …, 2025 - pmc.ncbi.nlm.nih.gov
Hepatitis B virus (HBV) infection causes acute and chronic hepatitis, compensated and
decompensated cirrhosis, and hepatocellular carcinoma worldwide. The actual status of …