Microfluidics: reframing biological enquiry

TA Duncombe, AM Tentori, AE Herr - Nature Reviews Molecular Cell …, 2015 - nature.com
The underlying physical properties of microfluidic tools have led to new biological insights
through the development of microsystems that can manipulate, mimic and measure biology …

High‐throughput DNA sequencing–concepts and limitations

M Kircher, J Kelso - Bioessays, 2010 - Wiley Online Library
Recent advances in DNA sequencing have revolutionized the field of genomics, making it
possible for even single research groups to generate large amounts of sequence data very …

Next-generation DNA sequencing

J Shendure, H Ji - Nature biotechnology, 2008 - nature.com
DNA sequence represents a single format onto which a broad range of biological
phenomena can be projected for high-throughput data collection. Over the past three years …

Microfluidic devices for bioapplications

LY Yeo, HC Chang, PPY Chan, JR Friend - small, 2011 - Wiley Online Library
Harnessing the ability to precisely and reproducibly actuate fluids and manipulate
bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful …

Digital microfluidics: is a true lab-on-a-chip possible?

RB Fair - Microfluidics and Nanofluidics, 2007 - Springer
The suitability of electrowetting-on-dielectric (EWD) microfluidics for true lab-on-a-chip
applications is discussed. The wide diversity in biomedical applications can be parsed into …

Lab-on-chip technologies: making a microfluidic network and coupling it into a complete microsystem—a review

P Abgrall, AM Gue - Journal of micromechanics and …, 2007 - iopscience.iop.org
Microfluidics is an emerging field that has given rise to a large number of scientific and
technological developments over the last few years. This review reports on the use of …

Integrated microfluidic devices

D Erickson, D Li - Analytica chimica acta, 2004 - Elsevier
“With the fundamentals of microscale flow and species transport well developed, the recent
trend in microfluidics has been to work towards the development of integrated devices which …

Micro total analysis systems. Recent developments

T Vilkner, D Janasek, A Manz - Analytical chemistry, 2004 - ACS Publications
The area of micro total analysis systems (μTAS), also called “lab on a chip” or miniaturized
analysis systems, is growing rapidly. This paper represents an update of the earlier reviews …

Disposable microfluidic devices: fabrication, function, and application

GS Fiorini, DT Chiu - BioTechniques, 2005 - Taylor & Francis
This review article describes recent developments in microfluidics, with special emphasis on
disposable plastic devices. Included is an overview of the common methods used in the …

Detecting biothreat agents: From current diagnostics to developing sensor technologies

SA Walper, G Lasarte Aragonés, KE Sapsford… - ACS …, 2018 - ACS Publications
Although a fundamental understanding of the pathogenicity of most biothreat agents has
been elucidated and available treatments have increased substantially over the past …