Review of the physicochemical methods applied in the investigation of the maillard reaction in pharmaceutical preparations

F Ghaderi, F Monajjemzadeh - Journal of Drug Delivery Science and …, 2020 - Elsevier
In recent years there has been an increasing interest in the study of drug-excipient
interactions in pharmaceutical dosage forms. Maillard reaction is one of the most important …

Bioinspired nickel oxide nanoparticle as an efficient nanocarrier in the delivery of doxorubicin as an anti-bladder cancer drug

YC Lv, EE Shahri, A Mahmoudi, RK Naughabi… - Inorganic Chemistry …, 2023 - Elsevier
This study introduces Cressa cretica plant extract as a green reducing and stabilizing agent
to prepare nickel oxide nanoparticles (NiO-NPs) from Ni (NO 3) 2· 6H 2 O using the sol–gel …

Delivery of anti-cancer and anti-depression doxepin drug by nickel oxide nanoparticles originated from the Cressa nudicaulis plant extract

Y Lu, M Han, EE Shahri, S Abbaspour, R Tayebee - RSC advances, 2023 - pubs.rsc.org
In this research, the extract of Cressa nudicaulis plant has been used as a natural reducing
agent in order to prepare stable nickel oxide nanoparticles (NiO NPs) using an aqueous …

Crystallization kinetics and glass-forming ability of rapidly crystallizing drugs studied by Fast Scanning Calorimetry

SE Lapuk, TA Mukhametzyanov, C Schick… - International Journal of …, 2021 - Elsevier
The use of the amorphous forms of drugs is a modern approach for the enhancement of
bioavailability. At the same time, the high cooling rate needed to obtain the metastable …

[PDF][PDF] Drug excipient compatibility testing protocols and charaterization: a review

KR Gupta, AR Pounikar, MJ Umekar - Asian J Chem Sci, 2019 - researchgate.net
Drug molecule contains various reactive functional groups which are susceptible to react
with another reactive functional groups which might be excipients, excipient or drugs …

Pharmaceutical compatibility of dexamethasone with excipients commonly used in solid oral dosage forms

WM Santos, FP Nóbrega, JC Andrade… - Journal of Thermal …, 2021 - Springer
Dexamethasone is a glucocorticoid drug used for the treatment of acute and chronic
inflammatory conditions, autoimmune diseases, some cancers, and several other …

In vitro genotoxic and cytotoxic effects of doxepin and escitalopram on human peripheral lymphocytes

H Cobanoglu, M Coskun, A Çayir… - Drug and Chemical …, 2018 - Taylor & Francis
Antidepressants are drugs used for the treatment of many psychiatric conditions including
depression. There are findings suggesting that these drugs might have genotoxic …

Decomposition kinetics of levofloxacin: drug-excipient interaction

J Nisar, M Iqbal, M Iqbal, A Shah, MS Akhter… - Zeitschrift für …, 2020 - degruyter.com
The present study is focused on the thermal decomposition of Levofloxacin in the absence
and presence of different excipients (sodium starch glycolate, magnesium stearate …

Compatibility study of theophylline with excipients using thermogravimetry supported by kinetic analysis

B Rojek, M Wesolowski - Journal of Thermal Analysis and Calorimetry, 2021 - Springer
Thermogravimetry was applied to a compatibility study between theophylline and excipients
such as glicocol, glucose, sorbitol, sucrose, cellulose and arabic gum. The technique is …

[HTML][HTML] Analytical investigation of the possible chemical interaction of methyldopa with some reducing carbohydrates used as pharmaceutical excipients

MR Siahi, S Rahimi… - Advanced Pharmaceutical …, 2018 - ncbi.nlm.nih.gov
Purpose: Assessment of drug substance and excipients compatibility is an important issue
during pre-formulation studies as well as the quality control of pharmaceutical dosage forms …