Understanding the pathophysiology of depression: From monoamines to the neurogenesis hypothesis model-are we there yet?

E Jesulola, P Micalos, IJ Baguley - Behavioural brain research, 2018 - Elsevier
A number of factors (biogenic amine deficiency, genetic, environmental, immunologic,
endocrine factors and neurogenesis) have been identified as mechanisms which provide …

Cortisol and major depressive disorder—translating findings from humans to animal models and back

LS Nandam, M Brazel, M Zhou, DJ Jhaveri - Frontiers in psychiatry, 2020 - frontiersin.org
Major depressive disorder (MDD) is a global problem for which current pharmacotherapies
are not completely effective. Hypothalamic–pituitary–adrenal (HPA) axis dysfunction has …

Neural correlates of dysfunctional emotion regulation in major depressive disorder. A systematic review of neuroimaging studies

MM Rive, G Van Rooijen, DJ Veltman… - Neuroscience & …, 2013 - Elsevier
Abnormal emotion processing is a core feature of major depressive disorder (MDD). Since
the emergence of functional neuroimaging techniques, many studies have been conducted …

Depression symptom dimensions as predictors of antidepressant treatment outcome: replicable evidence for interest-activity symptoms

R Uher, RH Perlis, N Henigsberg, A Zobel… - Psychological …, 2012 - cambridge.org
BackgroundSymptom dimensions have not yet been comprehensively tested as predictors
of the substantial heterogeneity in outcomes of antidepressant treatment in major depressive …

Aberrant topology of striatum's connectivity is associated with the number of episodes in depression

C Meng, F Brandl, M Tahmasian, J Shao, A Manoliu… - Brain, 2014 - academic.oup.com
In major depressive disorder, depressive episodes reoccur in∼ 60% of cases; however,
neural mechanisms of depressive relapse are poorly understood. Depressive episodes are …

Aberrant intrinsic connectivity of hippocampus and amygdala overlap in the fronto-insular and dorsomedial-prefrontal cortex in major depressive disorder

M Tahmasian, DC Knight, A Manoliu… - Frontiers in human …, 2013 - frontiersin.org
Neuroimaging studies of major depressive disorder (MDD) have consistently observed
functional and structural changes of the hippocampus (HP) and amygdale (AY). Thus, these …

The scanner as a stressor: evidence from subjective and neuroendocrine stress parameters in the time course of a functional magnetic resonance imaging session

M Muehlhan, U Lueken, HU Wittchen… - International journal of …, 2011 - Elsevier
Subjects participating in magnetic resonance imaging (MRI) examinations regularly report
anxiety and stress related reactions. This may result in impaired data quality and premature …

[HTML][HTML] Serotonergic modulation of intrinsic functional connectivity

A Schaefer, I Burmann, R Regenthal, K Arélin, C Barth… - Current Biology, 2014 - cell.com
Serotonin functions as an essential neuromodulator that serves a multitude of roles, most
prominently balancing mood [1]. Serotonergic challenge has been observed to reduce …

Neural correlates of altered general emotion processing in social anxiety disorder

AB Brühl, M Rufer, A Delsignore, T Kaffenberger… - Brain research, 2011 - Elsevier
Specific anxiety disorders are characterized by altered emotion processing of phobia-
specific stimuli at the neurobiological level. Recent work has concentrated on specific …

State-dependent differences in emotion regulation between unmedicated bipolar disorder and major depressive disorder

MM Rive, RJT Mocking, MWJ Koeter… - JAMA …, 2015 - jamanetwork.com
Importance Major depressive disorder (MDD) and bipolar disorder (BD) are difficult to
distinguish clinically during the depressed or remitted states. Both mood disorders are …