The role of microbiota in the development of colorectal cancer

Z Dai, J Zhang, Q Wu, J Chen, J Liu… - … journal of cancer, 2019 - Wiley Online Library
Colorectal cancer is the third largest cancer in worldwide and has been proven to be closely
related to the intestinal microbiota. Many reports and clinical studies have shown that …

Gut microbiota as important modulator of metabolism in health and disease

X Wang, A Zhang, J Miao, H Sun, G Yan, F Wu… - RSC …, 2018 - pubs.rsc.org
The human gastrointestinal tract colonizes a large number of microbial microflora, forms a
host-microbiota co-metabolism structure with the host to participate in various metabolic …

[HTML][HTML] Gut microbiome associated with APC gene mutation in patients with intestinal adenomatous polyps

S Liang, Y Mao, M Liao, Y Xu, Y Chen… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Background: The'adenoma-carcinoma sequence'is a well-recognized model of colorectal
cancer (CRC) development. However, the interaction between gut microbiota and genetic …

The influence of polyphenol compounds on human gastrointestinal tract microbiota

M Wiciński, J Gębalski, E Mazurek, M Podhorecka… - Nutrients, 2020 - mdpi.com
Polyphenols form a diverse group of compounds containing at least two hydroxyl groups in
their chemical structure. Because of the common presence in plant kingdom, polyphenols …

A synopsis of modern-day colorectal cancer: Where we stand

R Ranasinghe, M Mathai, A Zulli - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Colorectal cancer (CRC) is a malignancy in the gastro-intestinal (GI) tract which has very
limited treatment options still, despite the vast amount of research undertaken. CRC was first …

Chronic stress, inflammation, and colon cancer: a CRH system-driven molecular crosstalk

S Baritaki, E de Bree, E Chatzaki… - Journal of clinical …, 2019 - mdpi.com
Chronic stress is thought to be involved in the occurrence and progression of multiple
diseases, via mechanisms that still remain largely unknown. Interestingly, key regulators of …

The impact of polyphenol on general nutrient metabolism in the monogastric gastrointestinal tract

MS Swallah, H Fu, H Sun, R Affoh… - Journal of Food …, 2020 - Wiley Online Library
Polyphenols are bioactive compounds occurring in plant foods, which are considered
significant owing to their contribution to human health and the prevention of chronic …

Beyond a chemopreventive reagent, aspirin is a master regulator of the hallmarks of cancer

X Zhang, Y Feng, X Liu, J Ma, Y Li, T Wang… - Journal of Cancer …, 2019 - Springer
Purpose Aspirin, one of the most commonly used nonsteroidal anti-inflammatory drugs
(NAIDS), not only shows cancer chemoprevention effects but also improves cancer …

Association between the severity of metabolic dysfunction-associated fatty liver disease and the risk of colorectal neoplasm: a systematic review and meta-analysis

Y Zeng, R Cao, Z Tao, Y Gao - Lipids in Health and Disease, 2022 - Springer
Background The severity of metabolic dysfunction-associated fatty liver disease (MAFLD)
reportedly plays a part in the etiology of colorectal tumors. However, there is no consensus …

The role of vitamin D receptor gene polymorphisms in colorectal cancer risk

I Messaritakis, A Koulouridi, M Sfakianaki… - Cancers, 2020 - mdpi.com
Vitamin D deficiency has been associated with increased colorectal cancer (CRC) incidence
risk and mortality. Vitamin D mediates its action through the binding of the vitamin D receptor …