Oxidative stress in stem cell aging

F Chen, Y Liu, NK Wong, J Xiao, KF So - Cell transplantation, 2017 - journals.sagepub.com
Stem cell aging is a process in which stem cells progressively lose their ability to self-renew
or differentiate, succumb to senescence or apoptosis, and eventually become functionally …

The multiple functions of melatonin in regenerative medicine

M Majidinia, RJ Reiter, SK Shakouri, I Mohebbi… - Ageing research …, 2018 - Elsevier
Melatonin research has been experiencing hyper growth in the last two decades; this relates
to its numerous physiological functions including anti-inflammation, oncostasis, circadian …

AH2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II …

J Chen, L Chen, Y Wu, Y Fang, F Zeng, S Wu… - Nature …, 2021 - nature.com
Developing high-quality NIR-II fluorophores (emission in 1000–1700 nm) for in vivo imaging
is of great significance. Benzothiadiazole-core fluorophores are an important class of NIR-II …

[HTML][HTML] Intravenous administration of xenogenic adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes markedly reduced brain infarct …

KH Chen, CH Chen, CG Wallace, CM Yuen, GS Kao… - Oncotarget, 2016 - ncbi.nlm.nih.gov
We tested the hypothesis that combined xenogenic (from mini-pig) adipose-derived
mesenchymal stem cell (ADMSC) and ADMSC-derived exosome therapy could reduce brain …

Combination of adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes for protecting kidney from acute ischemia–reperfusion injury

KC Lin, HK Yip, PL Shao, SC Wu, KH Chen… - International journal of …, 2016 - Elsevier
Background In this study, we tested the hypothesis that a combined adipose-derived
mesenchymal stem cell (ADMSC) and ADMSC-derived exosome therapy protected rat …

Human umbilical cord-derived mesenchymal stem cells for acute respiratory distress syndrome

HK Yip, WF Fang, YC Li, FY Lee, CH Lee… - Critical care …, 2020 - journals.lww.com
Objectives: To investigate the safety, feasibility, and possible adverse events of single-dose
human umbilical cord-derived mesenchymal stem cells in patients with moderate-to-severe …

[HTML][HTML] Melatonin treatment improves mesenchymal stem cells therapy by preserving stemness during long-term in vitro expansion

Y Shuai, L Liao, X Su, Y Yu, B Shao, H Jing… - Theranostics, 2016 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are promising candidates for tissue regeneration and
disease treatment. However, long-term in vitro passaging leads to stemness loss of MSCs …

Melatonin plays critical role in mesenchymal stem cell-based regenerative medicine in vitro and in vivo

C Hu, L Li - Stem cell research & therapy, 2019 - Springer
Although stem cells have emerged as promising sources for regenerative medicine, there
are many potential safety hazards for their clinical application, including tumorigenicity, an …

Melatonin protects ADSC s from ROS and enhances their therapeutic potency in a rat model of myocardial infarction

P Zhu, J Liu, J Shi, Q Zhou, J Liu… - Journal of cellular …, 2015 - Wiley Online Library
Myocardial infarction (MI) is a major cause of death and disability worldwide. In the last
decade, mesenchymal stem cells (MSC s) based cell therapy has emerged as a promising …

Exosomes derived from mesenchymal stem cells: novel effects in the treatment of ischemic stroke

Y Xiong, J Song, X Huang, Z Pan… - Frontiers in …, 2022 - frontiersin.org
Ischemic stroke is defined as an infarction in the brain, caused by impaired cerebral blood
supply, leading to local brain tissue ischemia, hypoxic necrosis, and corresponding …