γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the vertebrate brain.
In the past, there has been a major research drive focused on the dysfunction of the …

Glutamate and GABA are the quantitatively major neurotransmitters in the brain mediating
excitatory and inhibitory signaling, respectively. These amino acids are metabolically …

Neuroinflammation with excess microglial activation and synaptic dysfunction are early
symptoms of most neurological diseases. However, how microglia-associated …

Background Glutamate and γ-aminobutyric acid (GABA) transporters play important roles in
balancing excitatory and inhibitory signals in the brain. Increasing evidence suggest that …

Technologies for mapping the spatial and temporal patterns of neural activity have
advanced our understanding of brain function in both health and disease. An important …

Abstract γ-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter in the nervous
system. It plays a crucial role in many physiological processes. Upon release from the …

γ-Aminobutyric acid (GABA) Transporters (GATs) belong to sodium and chloride dependent-
transporter family and are widely expressed throughout the brain. Notably, GAT1 is …

It is clear that normal neuronal function relies on a tight balance between excitatory and
inhibitory neurotransmission. Inhibitory signaling through the GABAergic system can be …

Epilepsy is a serious neurological disorder associated with recurrent and unpredictable
seizures and extensive neuropsychiatric comorbidities. There is no cure for epilepsy, and …

Abstract ɣ-aminobutyric-acid (GABA) functions as the principal inhibitory neurotransmitter in
the central nervous system. Imbalances in GABAergic neurotransmission are involved in the …