Use of chiral auxiliaries in the asymmetric synthesis of biologically active compounds: A review

G Diaz‐Muñoz, IL Miranda, SK Sartori… - Chirality, 2019 - Wiley Online Library
This review article describes the use of some of the most popular chiral auxiliaries in the
asymmetric synthesis of biologically active compounds. Chiral auxiliaries derived from …

Synthesis of nonracemic phosphonates

DF Wiemer - Tetrahedron, 1997 - Elsevier
1 Introduction. Phosphonic acids and their phosphonate derivatives are common in the
literature of organic chemistry where they are employed in synthetic operations leading to …

Organocopper reagents: substitution, conjugate addition, carbo/metallocupration, and other reactions

BH Lipshutz, S Sengupta - Organic Reactions, 2004 - Wiley Online Library
Well over a decade ago, two reviews were contributed to the Organic Reactions series
covering substitution and conjugate addition reactions in organocopper chemistry. Their …

Chapter Two Pyridine and piperidine alkaloids: An update

MJ Schneider - Alkaloids: Chemical and Biological Perspectives, 1996 - Elsevier
Publisher Summary This chapter provides an update on pyridine and piperidine alkaloids.
Cardiovascular effects of nicotine and cotinine have been studied. One study reported an …

Recent advances in the application of the Oppolzer camphorsultam as a chiral auxiliary

MM Heravi, V Zadsirjan - Tetrahedron: Asymmetry, 2014 - Elsevier
Oppolzer's camphorsultam has attracted much attention as an efficient chiral auxiliary, and is
one of the most powerful synthetic tools in asymmetric synthesis. The sultam chiral auxiliary …

. alpha.,. beta.-Unsaturated oxazolines, a powerful tool in asymmetric Diels-Alder cycloadditions

C Kouklovsky, A Pouilhes… - Journal of the American …, 1990 - ACS Publications
,/3-Unsaturated oxazolines 10, 12, and 16, activated with trifluoroacetic anhydride, proved to
be very powerful dienophiles toward various dienes suchas 17-23 including Danishefsky …

A convergent three-component total synthesis of the powerful immunosuppressant (−)-sanglifehrin A

LA Paquette, M Duan, I Konetzki… - Journal of the American …, 2002 - ACS Publications
The potent immunosuppressive agent (−)-sanglifehrin A (5), initially discovered in a soil
sample from Malawi, has been synthesized in a highly convergent and stereocontrolled …

Synthesis of Gly-ψ[(Z)CFCH]-Phe, a Fluoroalkene Dipeptide Isostere, and Its Incorporation into a Leu-enkephalin Peptidomimetic

JF Nadon, K Rochon, S Grastilleur… - ACS chemical …, 2017 - ACS Publications
A new Leu-enkephalin peptidomimetic designed to explore the hydrogen bond acceptor
ability of the third peptide bond has been prepared and studied. This new analog is …

[图书][B] Asymmetric synthetic methodology

DJ Ager, MB East - 2020 - taylorfrancis.com
This comprehensive text presents a critical discussion of the scopes and limitations of
various organic synthetic methodologies that are available for performing asymmetric …

Marine natural products

DJ Faulkner - Natural Product Reports, 1990 - pubs.rsc.org
This Report is a review of the literature of marine natural product chemistry for the period 1
December 1987 to the end of 1988. This is the sixth in a series of reviews published in …