A review on 'sulfonamides': their chemistry and pharmacological potentials for designing therapeutic drugs in medical science

W Zafar, SH Sumrra, AU Hassan… - Journal of Coordination …, 2023 - Taylor & Francis
The discovery of new chemical entities having enhanced bioactivities and improved
functionalities to overcome the prevailing antibiotic resistance and emerging diseases has …

Ultrasonic-assisted synthesis of benzofuran appended oxadiazole molecules as tyrosinase inhibitors: mechanistic approach through enzyme inhibition, molecular …

A Irfan, AF Zahoor, S Kamal, M Hassan… - International journal of …, 2022 - mdpi.com
Furan-oxadiazole structural hybrids belong to the most promising and biologically active
classes of oxygen and nitrogen containing five member heterocycles which have expanded …

Exploring anti-nonalcoholic fatty liver disease mechanism of Gardeniae Fructus by network pharmacology, molecular docking, and experiment validation

Z Tang, L Li, Z Xia - ACS omega, 2022 - ACS Publications
Gardeniae fructus (GF), the fruit from Gardenia jasminoides Ellis, is a traditional Chinese
medicine used for the treatment of nonalcoholic fatty liver disease (NAFLD) in the clinic. To …

Bioactive compounds from Pandanous fascicularis as potential therapeutic candidate to tackle hepatitis a inhibition: Docking and molecular dynamics simulation …

M Moharana, SK Pattanayak, F Khan - Journal of Biomolecular …, 2023 - Taylor & Francis
Due to extensive pharmacological research, medicinal plants the underpinning of
indigenous herbal serve as a possible source of key compounds for the development of new …

Identification and Verification of Potential Biomarkers in Renal Ischemia‐Reperfusion Injury by Integrated Bioinformatic Analysis

Z Pan, Y Yang, R Cao, Y Qiu, S Li… - BioMed Research …, 2023 - Wiley Online Library
Background. Renal ischemia‐reperfusion injury (RIRI) plays an important role in the poor
prognosis of patients with renal transplants. However, the potential targets and mechanism …

Investigation of the Mechanism of Action of Qingzaojiufei Decoction on Idiopathic Pulmonary Fibrosis Based on Network Pharmacology and Experimental Validation

C Mao, Y Du, K Niu, F Yang, C Bai… - Natural Product …, 2024 - journals.sagepub.com
Objective: The Traditional Chinese Medicine Qingzao Jiufei Tang decoction (QZJFD) is
effective for the treatment of idiopathic pulmonary fibrosis (IPF). In this study, we explored the …

Synthesis, Characterization and In silico Studies of Novel (E)-4-(((3-(substituted phenyl)-1-phenyl-1H-pyrazol-5-yl) methylene) amino) benzenesulfonamide as …

V PANCHAL, Z GADHAWALA… - Oriental Journal of …, 2024 - search.ebscohost.com
This research delves into the examination of benzene sulphonamide derivatives featuring
pyrazole rings as potential diuretics. Concentrating on their role as human carbonic …

[PDF][PDF] Alcoholic Extracts of Eleusine indica as Alternative Diuretic Regimens: A Computational Based Investigation

TK Sahu, N Sahoo, G Pattnaik, HB Samal… - Int. J. Exp. Res …, 2024 - researchgate.net
Diuretics are widely used in current clinical practice to increase urine production and excrete
electrolytes, particularly sodium and chloride ions, without affecting the absorption of protein …

Photoinduced electron transfer photodecomposition of 1, 4-Dihydropyridine derivative phototoxic drug Manidipine, Docking and Molecular Dynamic studies

SK Mustafa, M Al-Anazi, MMH Aljohani, N Omer… - 2024 - researchsquare.com
The present investigation focuses on the photochemical transformation of Manidipine (1)
using ultraviolet-A light while being accompanied by an electron-donating agent (Et 3 N) …