Covid-19 vaccines—immunity, variants, boosters
DH Barouch - New England Journal of Medicine, 2022 - Mass Medical Soc
Covid-19 Vaccines — Immunity, Variants, Boosters | NEJM Skip to main content NEJM Group
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SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact
M Lipsitch, F Krammer, G Regev-Yochay… - Nature Reviews …, 2022 - nature.com
Breakthrough infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in fully vaccinated individuals are receiving intense scrutiny because of their importance …
2) in fully vaccinated individuals are receiving intense scrutiny because of their importance …
Immunological mechanisms of vaccine-induced protection against COVID-19 in humans
M Sadarangani, A Marchant… - Nature Reviews …, 2021 - nature.com
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre …
G Zeng, Q Wu, H Pan, M Li, J Yang, L Wang… - The Lancet Infectious …, 2022 - thelancet.com
Background Large-scale vaccination against COVID-19 is being implemented in many
countries with CoronaVac, an inactivated vaccine. We aimed to assess the immune …
countries with CoronaVac, an inactivated vaccine. We aimed to assess the immune …
Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection
Predictive models of immune protection from COVID-19 are urgently needed to identify
correlates of protection to assist in the future deployment of vaccines. To address this, we …
correlates of protection to assist in the future deployment of vaccines. To address this, we …
SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients
D Geers, MC Shamier, S Bogers, G den Hartog… - Science …, 2021 - science.org
The emergence of SARS-CoV-2 variants harboring mutations in the spike (S) protein has
raised concern about potential immune escape. Here, we studied humoral and cellular …
raised concern about potential immune escape. Here, we studied humoral and cellular …
Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants
A Pegu, SE O'Connell, SD Schmidt, S O'Dell… - Science, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutations may diminish
vaccine-induced protective immune responses, particularly as antibody titers wane over …
vaccine-induced protective immune responses, particularly as antibody titers wane over …
Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination
mRNA vaccines for SARS-CoV-2 have been authorized for emergency use. Despite their
efficacy in clinical trials, data on mRNA vaccine–induced immune responses are mostly …
efficacy in clinical trials, data on mRNA vaccine–induced immune responses are mostly …
Antibody persistence through 6 months after the second dose of mRNA-1273 vaccine for Covid-19
N Doria-Rose, MS Suthar, M Makowski… - … England Journal of …, 2021 - Mass Medical Soc
Persistence of Antibody after mRNA-1273 Vaccination A total of 33 participants who
received both doses of the Moderna mRNA-1273 vaccine against SARS-CoV-2 had blood …
received both doses of the Moderna mRNA-1273 vaccine against SARS-CoV-2 had blood …
Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine
V Oberhardt, H Luxenburger, J Kemming, I Schulien… - Nature, 2021 - nature.com
SARS-CoV-2 spike mRNA vaccines,–mediate protection from severe disease as early as ten
days after prime vaccination, when neutralizing antibodies are hardly detectable,–. Vaccine …
days after prime vaccination, when neutralizing antibodies are hardly detectable,–. Vaccine …