Organ‐on‐a‐Chip Systems: microengineering to biomimic living systems

F Zheng, F Fu, Y Cheng, C Wang, Y Zhao, Z Gu - Small, 2016 - Wiley Online Library
“Organ‐on‐a‐chip” systems integrate microengineering, microfluidic technologies, and
biomimetic principles to create key aspects of living organs faithfully, including critical …

Structure and dynamics of interfacial peptides and proteins from vibrational sum-frequency generation spectroscopy

S Hosseinpour, SJ Roeters, M Bonn, W Peukert… - Chemical …, 2020 - ACS Publications
Proteins at interfaces play important roles in cell biology, immunology, bioengineering, and
biomimetic material design. Many biological processes are based on interfacial protein …

Immobilized enzymes: understanding enzyme–surface interactions at the molecular level

M Hoarau, S Badieyan, ENG Marsh - Organic & Biomolecular …, 2017 - pubs.rsc.org
Enzymes immobilized on solid supports have important and industrial and medical
applications. However, their uses are limited by the significant reductions in activity and …

[HTML][HTML] Hydration behaviors of nonfouling zwitterionic materials

P Sarker, T Lu, D Liu, G Wu, H Chen, MSJ Sajib… - Chemical …, 2023 - pubs.rsc.org
Zwitterionic materials have emerged as highly effective ultralow fouling materials for many
applications, however the underlying mechanism of fouling resistance remains unclear …

Probing orientations and conformations of peptides and proteins at buried interfaces

W Guo, T Lu, Z Gandhi, Z Chen - The Journal of Physical …, 2021 - ACS Publications
Molecular structures of peptides/proteins at interfaces determine their interfacial properties,
which play important roles in many applications. It is difficult to probe interfacial …

GRK2: multiple roles beyond G protein-coupled receptor desensitization

T Evron, TL Daigle, MG Caron - Trends in pharmacological sciences, 2012 - cell.com
G protein-coupled receptor kinases (GRKs) regulate numerous G protein-coupled receptors
(GPCRs) by phosphorylating the intracellular domain of the active receptor, resulting in …

Engineering and characterization of peptides and proteins at surfaces and interfaces: a case study in surface-sensitive vibrational spectroscopy

B Ding, J Jasensky, Y Li, Z Chen - Accounts of Chemical Research, 2016 - ACS Publications
Conspectus Understanding molecular structures of interfacial peptides and proteins impacts
many research fields by guiding the advancement of biocompatible materials, new and …

Control of protein conformation and orientation on graphene

S Wei, X Zou, J Tian, H Huang, W Guo… - Journal of the American …, 2019 - ACS Publications
Graphene-based biosensors have attracted considerable attention due to their advantages
of label-free detection and high sensitivity. Many such biosensors utilize noncovalent van …

Biomolecular structure at solid–liquid interfaces as revealed by nonlinear optical spectroscopy

S Roy, PA Covert, WR FitzGerald, DK Hore - Chemical reviews, 2014 - ACS Publications
1. INTRODUCTION The attachment of biomolecules onto solid surfaces is fundamental to a
wide range of scientific, engineering, and industrial pursuits. 1, 2 For example, the …

Molecular structure of the surface-immobilized super uranyl binding protein

W Guo, X Zou, H Jiang, KJ Koebke… - The Journal of …, 2021 - ACS Publications
Recently, a super uranyl binding protein (SUP) was developed, which exhibits excellent
sensitivity/selectivity to bind uranyl ions. It can be immobilized onto a surface in sensing …