Second and third-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumour activity

GV Suárez-Moreno, D Hernández-Romero… - Coordination Chemistry …, 2022 - Elsevier
The application of metal compounds in the medical field dates back to the XVI century with
some isolated reports about the therapeutic importance of metals and their compounds in …

A review on synthetic approaches of benzimidazoles

VAS Pardeshi, NS Chundawat, SI Pathan… - Synthetic …, 2021 - Taylor & Francis
From the group of heterocyclic compounds, benzimidazoles remain the central focus, which
owns the important features as six-five member attached rings having two nitrogen atoms at …

[HTML][HTML] Synthesis and characterization of different complexes derived from Schiff base and evaluation as a potential anticancer, antimicrobial, and insecticide agent

LM Aroua, SK Alhag, LA Al-Shuraym… - Saudi Journal of …, 2023 - Elsevier
The condensation of (1H-benzimidazole-2-yl) methanamine, with 2-hydroxy
naphthaldehyde lead to Schiff base ligand (H2L)(1). This was later reacted with metal salts …

Exploring the potential of metallodrugs as chemotherapeutics for triple negative breast cancer

N Nayeem, M Contel - Chemistry–A European Journal, 2021 - Wiley Online Library
This review focuses on studies of coordination and organometallic compounds as potential
chemotherapeutics against triple negative breast cancer (TNBC) which has one of the …

Importance of fluorine in benzazole compounds

T Al-Harthy, W Zoghaib, R Abdel-Jalil - Molecules, 2020 - mdpi.com
Fluorine-containing heterocycles continue to receive considerable attention due to their
unique properties. In medicinal chemistry, the incorporation of fluorine in small molecules …

Organometallic dendrimers based on Ruthenium (II) N-heterocyclic carbenes and their implication as delivery systems of anticancer small interfering RNA

T Rodriguez-Prieto, S Michlewska, M Hołota… - Journal of inorganic …, 2021 - Elsevier
With the purpose of obtaining a new dendritic system against cancer, this paper is focused
on the synthesis of spherical carbosilane metallodendrimers of different generations holding …

Ru(II)(ƞ6-p-cymene) Conjugates Loaded onto Graphene Oxide: An Effective pH-Responsive Anticancer Drug Delivery System

S Akhter, F Arjmand, C Pettinari, S Tabassum - Molecules, 2022 - mdpi.com
Graphene oxide-based nanodrug delivery systems are considered one of the most
promising platforms to deliver therapeutic drugs at the target site. In this study, Ru (II)(ƞ 6-p …

Selective Targeting of Regulated Rhabdomyosarcoma Cells by Trinuclear Ruthenium (II)–Arene Complexes

A Welsh, K Serala, S Prince… - Journal of Medicinal …, 2024 - ACS Publications
The use of benzimidazole-based trinuclear ruthenium (II)–arene complexes (1–3) to
selectively target the rare cancer rhabdomyosarcoma is reported. Preliminary cytotoxic …

[HTML][HTML] Aminoquinoline-based Re (I) tricarbonyl complexes: Insights into their antiproliferative activity and mechanisms of action

PS Zinman, A Welsh, RO Omondi, S Khan… - European Journal of …, 2024 - Elsevier
In an effort to develop new potent anticancer agents, two Schiff base rhenium (I) tricarbonyl
complexes, containing the ubiquitous aminoquinoline scaffold, were synthesized. Both …

Cytotoxicity evaluation of unmodified paddlewheel dirhodium (II, II)-acetate/-formamidinate complexes and their axially modified low-valent metallodendrimers

S de Doncker, E Fischer-Fodor, CI Vlad… - Molecules, 2023 - mdpi.com
Two diphenyl formamidine ligands, four dirhodium (II, II) complexes, and three axially
modified low-valent dirhodium (II, II) metallodendrimers were synthesized and evaluated as …