Matrix metalloproteinases (MMPs), also designated matnxms, are a family of related zinc
metalloendopeptidases that function in the turnover of components of the extracellular …

Kjær, Michael. Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to
Mechanical Loading. Physiol Rev 84: 649–698, 2004; 10.1152/physrev. 00031.2003.—The …

Angiogenesis, or the formation of new blood vessels from the preexisting vasculature, is a
key component in numerous physiologic and pathologic responses and has broad impact in …

Matrix metalloproteinases (MMPs) are a family of enzymes that proteolytically degrade
various components of the extracellular matrix (ECM). Angiogenesis is the process of …

Extracellular matrix (ECM) is essential for all stages of angiogenesis. In the adult,
angiogenesis begins with endothelial cell (EC) activation, degradation of vascular basement …

Phage that display a surface peptide with the NGR sequence motif home selectively to tumor
vasculature in vivo. A drug coupled to an NGR peptide has more potent antitumor effects …

Intimal thickening, the accumulation of cells and extracellular matrix within the inner vessel
wall, is a physiological response to mechanical injury, increased wall stress, or chemical …

See other articles in this series on pages 1227–1230 and 1231–1236 in this issue. in
amnionic membranes, fibrin clots, type I collagen, or basement membrane matrices. In these …

Extracellular proteolysis is an absolute requirement for new blood vessel formation
(angiogenesis). This review examines the role of the matrix metalloproteinase (MMP) and …

Cell migration in three-dimensional (3-D) extracellular matrix (ECM) is not a uniform event
but rather comprises a modular spectrum of interdependent biophysical and biochemical …