Access to device-aided therapies in advanced Parkinson's disease: navigating clinician biases, patient preference, and prognostic uncertainty

M Auffret, D Weiss, F Stocchi, M Vérin… - Journal of Neural …, 2023 - Springer
Abstract Device-aided therapies (DAT), which include deep brain stimulation and pump-
based continuous dopaminergic stimulation with either levodopa or apomorphine, are …

Immunity orchestrates a bridge in gut-brain axis of neurodegenerative diseases

Y Cheng, C Chen, F Zhang - Ageing Research Reviews, 2023 - Elsevier
Neurodegenerative diseases, in particular for Alzheimer's disease (AD), Parkinson's disease
(PD) and Multiple sclerosis (MS), are a category of diseases with progressive loss of …

Continuous subcutaneous foslevodopa/foscarbidopa in Parkinson's disease: Safety and efficacy results from a 12-month, single-arm, open-label, phase 3 study

J Aldred, E Freire-Alvarez, AV Amelin, A Antonini… - Neurology and …, 2023 - Springer
Introduction Foslevodopa/foscarbidopa, a soluble formulation of levodopa/carbidopa
(LD/CD) prodrugs for the treatment of Parkinson's disease (PD), is administered as a 24 …

Toward asleep DBS: cortico-basal ganglia spectral and coherence activity during interleaved propofol/ketamine sedation mimics NREM/REM sleep activity

J Guang, H Baker, O Ben-Yishay Nizri, S Firman… - npj Parkinson's …, 2021 - nature.com
Deep brain stimulation (DBS) is currently a standard procedure for advanced Parkinson's
disease. Many centers employ awake physiological navigation and stimulation assessment …

[HTML][HTML] Asleep DBS under ketamine sedation: Proof of concept

HB Erdman, E Kornilov, E Kahana, O Zarchi… - Neurobiology of …, 2022 - Elsevier
Background Deep brain stimulation (DBS) is commonly and safely performed for selective
Parkinson's disease patients. Many centers perform DBS lead positioning exclusively under …

Mapping the landscape of equitable access to advanced neurotechnologies in Canada

L Harding, J McFarlane, CR Honey… - Canadian Journal of …, 2023 - cambridge.org
Geographic, social, political, and economic factors shape access to advanced
neurotechnologies, yet little previous research has explored the barriers, enablers, and …

Interleaved Propofol‐Ketamine Maintains DBS Physiology and Hemodynamic Stability: A Double‐Blind Randomized Controlled Trial

E Kornilov, H Baker Erdman, E Kahana… - Movement …, 2024 - Wiley Online Library
Background The gold standard anesthesia for deep brain stimulation (DBS) surgery is the
“awake” approach, using local anesthesia alone. Although it offers high‐quality …

Deep brain stimulation surgery under ketamine induced conscious sedation: a double blind randomized controlled trial

E Kornilov, HB Erdman, E Kahana, S Fireman, O Zarchi… - medRxiv, 2023 - medrxiv.org
Background The gold standard anesthesia for deep brain stimulation (DBS) surgery is the
“awake” approach, using local anesthesia alone. While it offers high-quality microelectrode …

[HTML][HTML] Microelectrode assisted deep brain stimulation: Considerations for anesthesia

MLF Janssen, MJ Bos - Deep Brain Stimulation, 2024 - Elsevier
Deep brain stimulation (DBS) is a widely accepted and safe treatment for selected patients
with movement disorders. Many medical centres prefer to perform DBS lead positioning …

Minimising the rate of vascular complications in Deep Brain Stimulation surgery for the management of Parkinson's disease: a single-centre 600-patient case series

R Cook, NC Dutton, PA Silburn… - BMJ Neurology …, 2024 - pmc.ncbi.nlm.nih.gov
Abstract Objectives Deep Brain Stimulation (DBS) is an effective, yet underused therapy for
people living with Parkinson's disease (PD) in whom tremor, motor fluctuations and/or …