[HTML][HTML] Aging and age‐related diseases: from mechanisms to therapeutic strategies

Z Li, Z Zhang, Y Ren, Y Wang, J Fang, H Yue, S Ma… - Biogerontology, 2021 - Springer
Aging is a physiological process mediated by numerous biological and genetic pathways,
which are directly linked to lifespan and are a driving force for all age-related diseases …

Effects and mechanisms of resveratrol on aging and age‐related diseases

DD Zhou, M Luo, SY Huang, A Saimaiti… - Oxidative medicine …, 2021 - Wiley Online Library
The aging of population has become an issue of great concern because of its rapid
increase. Aging is an important risk factor of many chronic diseases. Resveratrol could be …

The effects of aging in the hippocampus and cognitive decline

LEB Bettio, L Rajendran, J Gil-Mohapel - Neuroscience & Biobehavioral …, 2017 - Elsevier
Aging is a natural process that is associated with cognitive decline as well as functional and
social impairments. One structure of particular interest when considering aging and …

Neuroprotective mechanisms of resveratrol in Alzheimer's disease: role of SIRT1

BAQ Gomes, JPB Silva, CFR Romeiro… - Oxidative medicine …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a progressive and neurodegenerative disorder of the cortex and
hippocampus, which eventually leads to cognitive impairment. Although the etiology of AD …

A comprehensive review of the health perspectives of resveratrol

A Rauf, M Imran, HAR Suleria, B Ahmad, DG Peters… - Food & function, 2017 - pubs.rsc.org
Many natural products present in our diet, including flavonoids, can prevent the progression
of cancer and other diseases. Resveratrol, a natural polyphenol present in various fruits and …

[HTML][HTML] Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

JA McCubrey, K Lertpiriyapong, LS Steelman… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
Natural products or nutraceuticals have been shown to elicit anti-aging, anti-cancer and
other health-enhancing effects. A key target of the effects of natural products may be the …

Ameliorative effects of resveratrol against cadmium-induced nephrotoxicity via modulating nuclear xenobiotic receptor response and PINK1/Parkin-mediated …

Q Zhang, C Zhang, J Ge, MW Lv, M Talukder, K Guo… - Food & function, 2020 - pubs.rsc.org
Cadmium (Cd) is a toxic pollutant with high nephrotoxicity in the agricultural environment.
Resveratrol has been found to have a renoprotective effect but the underlying mechanisms …

Resveratrol and brain mitochondria: a review

FR Jardim, FT de Rossi, MX Nascimento… - Molecular …, 2018 - Springer
Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …

[HTML][HTML] Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury

EN Kim, JH Lim, MY Kim, TH Ban, IA Jang… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
Background. Two important issues in the aging kidney are mitochondrial dysfunction and
oxidative stress. An Nrf2 activator, resveratrol, is known to have various effects. Resveratrol …

Turning back time with emerging rejuvenation strategies

S Mahmoudi, L Xu, A Brunet - Nature cell biology, 2019 - nature.com
Ageing is associated with the functional decline of all tissues and a striking increase in many
diseases. Although ageing has long been considered a one-way street, strategies to delay …