Viscoelastic hemostatic assays for postpartum hemorrhage

AE Liew-Spilger, NR Sorg, TJ Brenner… - Journal of Clinical …, 2021 - mdpi.com
This article discusses the importance and effectiveness of viscoelastic hemostatic assays
(VHAs) in assessing hemostatic competence and guiding blood component therapy (BCT) in …

Connecting the dots: exploring the interplay between preeclampsia and peripartum cardiomyopathy

KE Gumilar, KA Rauf, MIA Akbar… - Journal of …, 2024 - Wiley Online Library
Preeclampsia and peripartum cardiomyopathy (PPCM) are significant obstetric problems
that can arise during or after pregnancy. Both are known to be causes of maternal mortality …

First-trimester proteomic profiling identifies novel predictors of gestational diabetes mellitus

T Ravnsborg, S Svaneklink, LLT Andersen, MR Larsen… - PloS one, 2019 - journals.plos.org
Background Gestational diabetes mellitus (GDM) is a common pregnancy complication
associated with adverse outcomes including preeclampsia, caesarean section, macrosomia …

Fibrinolytic changes in women with preeclampsia

AC Godtfredsen, JJ Sidelmann… - Clinical and Applied …, 2022 - journals.sagepub.com
Objectives Preeclampsia (PE) is a serious complication of pregnancy. The fibrinolytic system
play crucial roles regarding placentation and evolution of PE. Aim To study comprehensively …

Plasma biomarkers for the identification of women at risk for early-onset preeclampsia

A Kolialexi, GT Tsangaris, S Sifakis… - Expert review of …, 2017 - Taylor & Francis
Background: To identify potential biomarkers in the 1st trimester of pregnancy for the
identification of women destined to develop early onset preeclampsia (EOPE). Methods …

The role of plasminogen activator inhibitor type 1 (PAI-1) in placenta-mediated pregnancy complications: a systematic review

I Agersnap, PH Nissen, AM Hvas - Seminars in Thrombosis …, 2022 - thieme-connect.com
Plasminogen activator inhibitor type 1 (PAI-1) is a main inhibitor of fibrinolysis. The PAI-1
gene (SERPINE1) harbors genetic variants with the potential of modifying plasma levels of …

Alpha-1-antitrypsin suppresses oxidative stress in preeclampsia by inhibiting the p38MAPK signaling pathway: An in vivo and in vitro study

YL Feng, YX Yin, J Ding, H Yuan, L Yang, JJ Xu… - PLoS …, 2017 - journals.plos.org
This present study was designed to investigate the effects of alpha-1-antitrypsin (AAT) on
oxidative stress in preeclampsia (PE) by regulating p38 mitogen-activated protein kinase …

Angiogenic imbalance and inflammatory biomarkers in the prediction of hypertension as well as obstetric and perinatal complications in women with gestational …

A Lara-Barea, B Sánchez-Lechuga… - Journal of Clinical …, 2022 - mdpi.com
Gestational diabetes mellitus (GDM) increases the risk of hypertensive disorders of
pregnancy (HDP). We aimed to analyze the altered inflammatory markers and angiogenic …

Late first trimester circulating microparticle proteins predict the risk of preeclampsia< 35 weeks and suggest phenotypic differences among affected cases

TF McElrath, DE Cantonwine, KJ Gray, H Mirzakhani… - Scientific reports, 2020 - nature.com
We hypothesize that first trimester circulating micro particle (CMP) proteins will define
preeclampsia risk while identifying clusters of disease subtypes among cases. We …

Lipid profile and cytokines in hypertension of pregnancy: A comparison of preeclampsia therapies

Y Wang, D Shi, L Chen - The Journal of Clinical Hypertension, 2018 - Wiley Online Library
Hypertensive disorders complicating pregnancy can be classified as gestational
hypertension, mild preeclampsia, and severe preeclampsia. It is necessary to evaluate and …