[HTML][HTML] Hierarchical eco-evo dynamics mediated by the gut microbiome

E Decaestecker, B Van de Moortel, S Mukherjee… - Trends in Ecology & …, 2024 - cell.com
The concept of eco-evolutionary (eco-evo) dynamics, stating that ecological and
evolutionary processes occur at similar time scales and influence each other, has …

[HTML][HTML] Modeling approaches for probing cross-feeding interactions in the human gut microbiome

P Saa, A Urrutia, C Silva-Andrade, AJ Martín… - Computational and …, 2022 - Elsevier
Microbial communities perform emergent activities that are essentially different from those
carried by their individual members. The gut microbiome and its metabolites have a …

Statistical and machine learning techniques in human microbiome studies: contemporary challenges and solutions

I Moreno-Indias, L Lahti, M Nedyalkova… - Frontiers in …, 2021 - frontiersin.org
The human microbiome has emerged as a central research topic in human biology and
biomedicine. Current microbiome studies generate high-throughput omics data across …

Metabolic models of human gut microbiota: Advances and challenges

DR Garza, D Gonze, H Zafeiropoulos, B Liu, K Faust - Cell systems, 2023 - cell.com
The human gut is a complex ecosystem consisting of hundreds of microbial species
interacting with each other and with the human host. Mathematical models of the gut …

Colon or semicolon: gut sampling microdevices for omics insights

S Nagpal, SK Srivastava - npj Biofilms and Microbiomes, 2024 - nature.com
Ingestible microdevices represent a breakthrough in non-invasive sampling of the human
gastrointestinal (GI) tract. By capturing the native spatiotemporal microbiome and intricate …

Metabolic interactions shape emergent biofilm structures in a conceptual model of gut mucosal bacterial communities

A Valiei, A Dickson, J Aminian-Dehkordi… - npj Biofilms and …, 2024 - nature.com
The gut microbiome plays a major role in human health; however, little is known about the
structural arrangement of microbes and factors governing their distribution. In this work, we …

In vitro human gastrointestinal tract simulation systems: a panoramic review

Y Dixit, K Kanojiya, N Bhingardeve, JJ Ahire… - Probiotics and …, 2024 - Springer
Simulated human gastrointestinal (GI) tract systems are important for their applications in the
fields of probiotics, nutrition and health. To date, various in vitro gut systems have been …

Agent based models of polymicrobial biofilms and the microbiome—A review

S Koshy-Chenthittayil, L Archambault, D Senthilkumar… - Microorganisms, 2021 - mdpi.com
The human microbiome has been a focus of intense study in recent years. Most of the living
organisms comprising the microbiome exist in the form of biofilms on mucosal surfaces …

Artichoke pectic oligosaccharide characterisation and virtual screening of prebiotic properties using in silico colonic fermentation

C Sabater, A Blanco-Doval, A Margolles, N Corzo… - Carbohydrate …, 2021 - Elsevier
The aim of this work was to develop a comprehensive workflow to elucidate molecular
features of artichoke pectic oligosaccharides (POS) contributing to high potential prebiotic …

Computational modeling of the human microbiome

S Chowdhury, SS Fong - Microorganisms, 2020 - mdpi.com
The impact of microorganisms on human health has long been acknowledged and studied,
but recent advances in research methodologies have enabled a new systems-level …