MicroRNA dysregulation in Parkinson's disease: a narrative review

YH Nies, NH Mohamad Najib, WL Lim… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is a severely debilitating neurodegenerative disease, affecting the
motor system, leading to resting tremor, cogwheel rigidity, bradykinesia, walking and gait …

Experimental approaches for manipulating choroid plexus epithelial cells

A Jang, MK Lehtinen - Fluids and barriers of the CNS, 2022 - Springer
Choroid plexus (ChP) epithelial cells are crucial for the function of the blood-cerebrospinal
fluid barrier (BCSFB) in the developing and mature brain. The ChP is considered the primary …

Schaftoside suppresses pentylenetetrazol-induced seizures in zebrafish via suppressing apoptosis, modulating inflammation, and oxidative stress

J Dang, YN Paudel, X Yang, Q Ren… - ACS chemical …, 2021 - ACS Publications
The lack of disease-modifying therapeutic strategies against epileptic seizures has caused a
surge in preclinical research focused on exploring and developing novel therapeutic …

Parkinson's disease model in zebrafish using intraperitoneal MPTP injection

NA Omar, J Kumar, SL Teoh - Frontiers in Neuroscience, 2023 - frontiersin.org
Introduction Parkinson's disease (PD) is the second most common neurodegenerative
disease that severely affects the quality of life of patients and their family members …

Zebrafish is a powerful tool for precision medicine approaches to neurological disorders

K Ochenkowska, A Herold, É Samarut - Frontiers in Molecular …, 2022 - frontiersin.org
Personalized medicine is currently one of the most promising tools which give hope to
patients with no suitable or no available treatment. Patient-specific approaches are …

The molecular mechanism of three novel peptides from C-phycocyanin alleviates MPTP-induced Parkinson's disease-like pathology in zebrafish

F Xu, Y Qiu, Y Zhang, F Yang, M Ji, K Liu, M Jin… - Food & Function, 2023 - pubs.rsc.org
Previous studies have shown that peptides isolated from C-phycocyanin (C-PC) possess
various functions including antioxidant and anticancer activities. However, there is little …

Zebrafish: A pharmacological model for learning and memory research

JK Tan, FH Nazar, S Makpol, SL Teoh - Molecules, 2022 - mdpi.com
Learning and memory are essential to organism survival and are conserved across various
species, especially vertebrates. Cognitive studies involving learning and memory require …

Neuroprotective effects of Neurotrophin-3 in MPTP-induced zebrafish Parkinson's disease model

NA Omar, J Kumar, SL Teoh - Frontiers in Pharmacology, 2023 - frontiersin.org
Introduction: Neurotrophin-3 (NT3) is a neuroprotective growth factor that induces the
development, maintenance and survival of neurons. This study aims to localize NT3 …

Longitudinal MRI brain studies in live adult zebrafish

N Hamilton, C Allen, S Reynolds - NMR in Biomedicine, 2023 - Wiley Online Library
Zebrafish (Danio rerio) has been successfully used for decades in developmental studies
and disease modelling. The remarkable uptake of zebrafish as a model system is partly due …

The effects of metallothionein in paraquat-induced Parkinson disease model of zebrafish

NH Mohamad Najib, MF Yahaya, S Das… - International Journal of …, 2023 - Taylor & Francis
Introduction Parkinson's disease (PD) is the second most common neurodegenerative
disease caused by selective degeneration of dopaminergic neurons in the substantia nigra …