Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Diabetic nephropathy (DN) often leads to end-stage renal disease. Oxidative stress
demonstrates a crucial act in the onset and progression of DN, which triggers various …

Diabetic nephropathy is one of the most common complications in diabetes. It has been
shown to be the leading cause of end-stage renal disease. However, due to their complex …

Various studies, especially in recent years, have shown that quercetin has beneficial
therapeutic effects in various human diseases, including diabetes. Quercetin has significant …

The physiological functions and bioavailability of flavonoids have been widely investigated
since their bioactivities were identified about 80 years ago. Quercetin is a typical flavonoid …

With the advances in biomedical technologies, natural products have attracted substantial
public attention in the area of drug discovery. Flavonoids are a class of active natural …

Quercetin, a flavonoid possessing numerous biological activities, is reported to improve
renal injury in diabetic animals. Here, the aim of this systematic review and meta-analysis is …

Type 2 diabetes mellitus is a disease that affects many metabolic pathways. It is associated
with insulin resistance, impaired insulin signaling, β-cell dysfunction, abnormal glucose …

Metabolic syndrome as a clustering disorder includes excess abdominal fat distribution,
abnormal insulin and glucose metabolism, disturbed blood lipids, pro-inflammatory state …

The disequilibrium between the production of reactive oxygen (ROS) and nitrogen (RNS)
species and their elimination by protective mechanisms leads to oxidative stress …