Gut-liver axis: Pathophysiological concepts and clinical implications

H Tilg, TE Adolph, M Trauner - Cell metabolism, 2022 - cell.com
Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …

Gut microbiota and short chain fatty acids: implications in glucose homeostasis

P Portincasa, L Bonfrate, M Vacca… - International journal of …, 2022 - mdpi.com
Gut microbiota encompasses a wide variety of commensal microorganisms consisting of
trillions of bacteria, fungi, and viruses. This microbial population coexists in symbiosis with …

Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients

D Davar, AK Dzutsev, JA McCulloch, RR Rodrigues… - Science, 2021 - science.org
Anti–programmed cell death protein 1 (PD-1) therapy provides long-term clinical benefits to
patients with advanced melanoma. The composition of the gut microbiota correlates with anti …

Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?

A Santoro, E Bientinesi, D Monti - Ageing research reviews, 2021 - Elsevier
During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

Macronutrient metabolism by the human gut microbiome: major fermentation by-products and their impact on host health

K Oliphant, E Allen-Vercoe - Microbiome, 2019 - Springer
The human gut microbiome is a critical component of digestion, breaking down complex
carbohydrates, proteins, and to a lesser extent fats that reach the lower gastrointestinal tract …

Metabolism and metabolic disorders and the microbiome: the intestinal microbiota associated with obesity, lipid metabolism, and metabolic health—pathophysiology …

J Aron-Wisnewsky, MV Warmbrunn, M Nieuwdorp… - Gastroenterology, 2021 - Elsevier
Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …

The gut microbiota at the intersection of diet and human health

CL Gentile, TL Weir - Science, 2018 - science.org
Diet affects multiple facets of human health and is inextricably linked to chronic metabolic
conditions such as obesity, type 2 diabetes, and cardiovascular disease. Dietary nutrients …

Regulation of intestinal lipid metabolism: current concepts and relevance to disease

CW Ko, J Qu, DD Black, P Tso - Nature Reviews Gastroenterology & …, 2020 - nature.com
Lipids entering the gastrointestinal tract include dietary lipids (triacylglycerols, cholesteryl
esters and phospholipids) and endogenous lipids from bile (phospholipids and cholesterol) …

Gut microbiota Turicibacter strains differentially modify bile acids and host lipids

JB Lynch, EL Gonzalez, K Choy, KF Faull… - Nature …, 2023 - nature.com
Bacteria from the Turicibacter genus are prominent members of the mammalian gut
microbiota and correlate with alterations in dietary fat and body weight, but the specific …

[HTML][HTML] Mechanism of the gut microbiota colonization resistance and enteric pathogen infection

I Khan, Y Bai, L Zha, N Ullah, H Ullah… - Frontiers in Cellular …, 2021 - frontiersin.org
The mammalian gut microbial community, known as the gut microbiota, comprises trillions of
bacteria, which co-evolved with the host and has an important role in a variety of host …