The pathogenesis of idiopathic pulmonary fibrosis (IPF) involves a complex interplay of cell
types and signaling pathways. Recurrent alveolar epithelial cell (AEC) injury may occur in …

Fibrosis is the final common pathway of inflammatory diseases in various organs. The
inflammasomes play an important role in the progression of fibrosis as innate immune …

The severity and outcome of coronavirus disease 2019 (COVID-19) largely depends on a
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …

A subset of individuals who recover from coronavirus disease 2019 (COVID-19) develop
post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Age-associated chronic inflammation is characterized by unresolved and uncontrolled
inflammation with multivariable low-grade, chronic and systemic responses that exacerbate …

Although fibrosis is a common pathological feature of most end-stage organ diseases, its
pathogenesis remains unclear. There is growing evidence that mitochondrial dysfunction …

Numerous compounds have shown efficacy in limiting development of pulmonary fibrosis
using animal models, yet few of these compounds have replicated these beneficial effects in …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly pathogenic
novel virus that has caused a massive pandemic called coronavirus disease 2019 (COVID …

Arthrofibrosis is a fibrotic joint disorder that begins with an inflammatory reaction to insults
such as injury, surgery and infection. Excessive extracellular matrix and adhesions contract …

Introduction: The novel coronavirus pandemic has caused significant mortality throughout
the world. This study was done as there is scarce data on mortality predictors in severe …