Immunotherapy has emerged as a promising treatment paradigm for many malignancies
and is transforming the drug development landscape. Although immunotherapeutic agents …

Despite advances in the diagnostic and therapeutic modalities, the prognosis of several
solid tumor malignancies remains poor. Different factors associated with solid tumors …

Glioblastoma is the most common brain malignant tumor in the adult population, and
immunotherapy is playing an increasingly central role in the treatment of many cancers …

Due to the refractory and partial sensitive treatments to malignant cancers, immunotherapy
has increasingly become a hotspot in effective anti-tumor research. However, at present …

Natural killer (NK) cells are the key immune effectors with the ability to mediate selection and
differentiation of a number of different cancer stem cells/undifferentiated tumors via lysis, and …

Background Natural killer (NK) cells can recognize and kill cancer cells directly, but their
activity can be attenuated by various inhibitory molecules expressed on the surface. The …

Introduction and methods In this study we report that sequential treatment of supercharged
NK (sNK) cells with either chemotherapeutic drugs or check-point inhibitors eliminate both …

In treatments of solid tumors, adoptive transfer of ex vivo expanded natural killer (NK) cells
has dawned as a new paradigm. Compared with cytotoxic T lymphocytes, NK cells take a …

Glioblastomas remain the most lethal primary brain tumors. Natural killer (NK) cell-based
therapy is a promising immunotherapeutic strategy in the treatment of glioblastomas, since …

Cancer immunotherapy is a highly successful and rapidly evolving treatment modality that
works by augmenting the body's own immune system. While various immune stimulation …