Epidemiology and Genetics of cystic fibrosis in a SIA: in preparation for the Next‐Generation treatments

M Singh, C Rebordosa, J Bernholz, N Sharma - Respirology, 2015 - Wiley Online Library
Cystic fibrosis (CF) in the A sian population is less frequently reported due to under‐
diagnosis and lack of centralized CF patient registries. Clinical studies on CF cases from A …

Genetic diversity among the Arabs

AS Teebi, SA Teebi - Public Health Genomics, 2005 - karger.com
The Arabs in general are genetically diverse. Major factors that contributed to their diversity
include the migrations of Semitic tribes from the Arabian Peninsula, the Islamic expansion in …

Newborn screening: experiences in the Middle East and North Africa

AA Saadallah, MS Rashed - Journal of inherited metabolic disease, 2007 - Springer
This review presents the current experiences with newborn screening in the Middle East and
North Africa region. The population in the region is about 400 million, with high birth rate and …

[HTML][HTML] Analysis of the CFTR gene in Iranian cystic fibrosis patients: identification of eight novel mutations

R Alibakhshi, R Kianishirazi, JJ Cassiman… - Journal of cystic …, 2008 - Elsevier
BACKGROUND: Cystic fibrosis (CF) is the most common inherited disorder in Caucasian
populations, with over 1400 mutations identified in the Cystic Fibrosis Transmembrane …

Spectrum of mutations of cystic fibrosis in the 22 Arab countries: A systematic review

D Al‐Sadeq, T Abunada, R Dalloul, S Fahad… - …, 2019 - Wiley Online Library
Cystic fibrosis (CF) is an autosomal recessive genetic disease caused by mutations in the
CFTR gene, with various clinical manifestations that affect pulmonary, digestive, exocrine …

[HTML][HTML] The road for survival improvement of cystic fibrosis patients in Arab countries

H Banjar, G Angyalosi - International Journal of Pediatrics and Adolescent …, 2015 - Elsevier
Cystic fibrosis (CF) is a lethal, monogenic disorder that affects multiple organ systems of the
body. The incidence has been described before in the Middle East to be 1 in 2000 to 1 in …

Genotype patterns for mutations of the cystic fibrosis transmembrane conductance regulator gene: a retrospective descriptive study from Saudi Arabia

HH Banjar, L Tuleimat, AAA El Seoudi… - Annals of Saudi …, 2020 - annsaudimed.net
ABSTRACT BACKGROUND: Cystic fibrosis (CF) occurs in populations in Saudi Arabia and
the Gulf area. Approximately 2000 known variants have been identified for the CF …

[HTML][HTML] Mutational spectrum of cystic fibrosis in the Lebanese population

C Farra, R Menassa, J Awwad, Y Morel… - Journal of cystic …, 2010 - Elsevier
BACKGROUND: Cystic fibrosis (CF) is the most common autosomal recessive disease in
Caucasians; it is however, considered to be rare in the Arab populations. Reports of the …

Mutation spectrum in Jewish cystic fibrosis patients in Israel: implication to carrier screening

A Quint, I Lerer, M Sagi… - American journal of …, 2005 - Wiley Online Library
We have tested 144 unrelated Jewish patients suffering from the classical form of cystic
fibrosis. The patients were screened for a panel of 12 mutations including the six Ashkenazi …

[HTML][HTML] Profile of cystic fibrosis in a single referral center in Egypt

MM El-Falaki, WA Shahin, NR El-Basha, AA Ali… - Journal of Advanced …, 2014 - Elsevier
It was generally believed that Cystic fibrosis (CF) is rare among Arabs; however, the few
studies available from Egypt and other Arabic countries suggested the presence of many …