Sex differences in the physiology of eating

L Asarian, N Geary - American Journal of Physiology …, 2013 - journals.physiology.org
Hypothalamic-pituitary-gonadal (HPG) axis function fundamentally affects the physiology of
eating. We review sex differences in the physiological and pathophysiological controls of …

Regulation of stress response on the hypothalamic-pituitary-gonadal axis via gonadotropin-inhibitory hormone

YL Son, T Ubuka, K Tsutsui - Frontiers in Neuroendocrinology, 2022 - Elsevier
Under stressful condition, reproductive function is impaired due to the activation of various
components of the hypothalamic–pituitaryadrenal (HPA) axis, which can suppress the …

Identification, expression, and physiological functions of Siberian hamster gonadotropin-inhibitory hormone

T Ubuka, K Inoue, Y Fukuda, T Mizuno, K Ukena… - …, 2012 - academic.oup.com
Gonadotropin-inhibitory hormone (GnIH) is a hypothalamic neuropeptide that inhibits
gonadotropin secretion in birds and mammals. To further understand its physiological roles …

Developmental variations in environmental influences including endocrine disruptors on pubertal timing and neuroendocrine control: revision of human observations …

AS Parent, D Franssen, J Fudvoye, A Gerard… - Frontiers in …, 2015 - Elsevier
Puberty presents remarkable individual differences in timing reaching over 5 years in
humans. We put emphasis on the two edges of the age distribution of pubertal signs in …

Gonadotropin-inhibitory hormone (GnIH) and its control of central and peripheral reproductive function

K Tsutsui, GE Bentley, G Bedecarrats, T Osugi… - Frontiers in …, 2010 - Elsevier
Identification of novel neurohormones that regulate the reproductive axis is essential for the
progress of neuroendocrinology. The decapeptide gonadotropin-releasing hormone (GnRH) …

Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis

T Ubuka, K Morgan, AJ Pawson, T Osugi… - PloS one, 2009 - journals.plos.org
The existence of a hypothalamic gonadotropin-inhibiting system has been elusive. A
neuropeptide named gonadotropin-inhibitory hormone (GnIH, SIKPSAYLPLRF-NH2) which …

Gonadotropin-inhibitory hormone (GnIH): discovery, progress and prospect

K Tsutsui, T Ubuka, GE Bentley, LJ Kriegsfeld - General and comparative …, 2012 - Elsevier
A hypothalamic neuropeptide, gonadotropin-releasing hormone (GnRH), is the primary
factor regulating gonadotropin secretion. An inhibitory hypothalamic neuropeptide for …

RFamide-related peptide-3 receptor gene expression in GnRH and kisspeptin neurons and GnRH-dependent mechanism of action

MZ Rizwan, MC Poling, M Corr, PA Cornes… - …, 2012 - academic.oup.com
RFamide-related peptide-3 (RFRP-3) is known to inhibit the activity of GnRH neurons. It is
not yet clear whether its G protein-coupled receptors, GPR147 and GPR74, are present on …

Discovery and evolutionary history of gonadotrophin‐inhibitory hormone and kisspeptin: new key neuropeptides controlling reproduction

K Tsutsui, GE Bentley, LJ Kriegsfeld… - Journal of …, 2010 - Wiley Online Library
Gonadotrophin‐releasing hormone (GnRH) is the primary hypothalamic factor responsible
for the control of gonadotrophin secretion in vertebrates. However, within the last decade …

Gonadotropin-inhibitory hormone is a hypothalamic peptide that provides a molecular switch between reproduction and feeding

IJ Clarke, JT Smith, BA Henry, BJ Oldfield… - …, 2012 - karger.com
Objective: Gonadotropin-inhibitory hormone (GnIH)-3 is a neuropeptide that plays a major
role in the regulation of reproduction and feeding in mammals. Materials and Methods: We …