To establish and maintain their polarized morphology, neurons employ active transport
driven by cytoskeletal motor proteins to sort cargo between axons and dendrites. These …

Myosins are a large family of actin-based cytoskeletal motors that use energy derived from
ATP hydrolysis to generate movement and force. Myosins of classes II, V and VI have …

Background Proteinaceous toxins are observed across all levels of inter-organismal and
intra-genomic conflicts. These include recently discovered prokaryotic polymorphic toxin …

The kinesin-3 family is one of the largest among the kinesin superfamily and its members
play important roles in a wide range of cellular transport activities, yet the molecular …

Three types of motors, myosins, kinesins, and cytoplasmic dynein, cooperate to transport
intracellular membrane organelles. Transport of each cargo is determined by recruitment of …

Members of the myosin superfamily are actin-based molecular motors that are
indispensable for cellular homeostasis. The vast functional and structural diversity of …

The delivery of intracellular material within cells is crucial for maintaining normal function.
Myosins transport a wide variety of cargo, ranging from vesicles to ribonuclear protein …

Myosin-X (Myo10) is an unconventional myosin with MyTH4-FERM domains that is best
known for its striking localization to the tips of filopodia and its ability to induce filopodia …

Unconventional myosins are a superfamily of actin-based motors implicated in diverse
cellular processes. In recent years, much progress has been made in describing their …

The coordinated trafficking and tethering of membrane cargo within cells relies on the
function of distinct cytoskeletal motors that are targeted to specific subcellular compartments …