Dual-specificity, tyrosine phosphorylation-regulated kinases (DYRKs) and cdc2-like kinases (CLKs) in human disease, an overview
MF Lindberg, L Meijer - International Journal of Molecular Sciences, 2021 - mdpi.com
Dual-specificity tyrosine phosphorylation-regulated kinases (DYRK1A, 1B, 2-4) and cdc2-
like kinases (CLK1-4) belong to the CMGC group of serine/threonine kinases. These protein …
like kinases (CLK1-4) belong to the CMGC group of serine/threonine kinases. These protein …
Flavonoids as promising antiviral agents against SARS-CoV-2 infection: a mechanistic review
A newly diagnosed coronavirus in 2019 (COVID-19) has affected all human activities since
its discovery. Flavonoids commonly found in the human diet have attracted a lot of attention …
its discovery. Flavonoids commonly found in the human diet have attracted a lot of attention …
[HTML][HTML] Traditional Chinese medicines as effective agents against influenza virus-induced pneumonia
M Yang, Y Wang, Y Yue, L Liang, M Peng… - Biomedicine & …, 2022 - Elsevier
Influenza virus-induced pneumonia (IVP) is a high morbidity and contagiousness pulmonary
infectious disease caused by invasion of the influenza virus into the lower respiratory tract …
infectious disease caused by invasion of the influenza virus into the lower respiratory tract …
Specialized metabolites from plants as a source of new multi-target antiviral drugs: a systematic review
M Ponticelli, ML Bellone, V Parisi, A Iannuzzi… - Phytochemistry …, 2023 - Springer
Viral infections have always been the main global health challenge, as several potentially
lethal viruses, including the hepatitis virus, herpes virus, and influenza virus, have affected …
lethal viruses, including the hepatitis virus, herpes virus, and influenza virus, have affected …
A critical update on the strategies towards small molecule inhibitors targeting Serine/arginine-rich (SR) proteins and Serine/arginine-rich proteins related kinases in …
J Tang, Y Xie, J Huang, L Zhang, W Jiang, Z Li… - Bioorganic & Medicinal …, 2022 - Elsevier
90% of genes in the human body undergo alternative splicing (AS) after transcription, which
enriches protein species and regulates protein levels. However, there is growing evidence …
enriches protein species and regulates protein levels. However, there is growing evidence …
Substantial effect of phytochemical constituents against the pandemic disease influenza—a review
AB Devi, R Sarala - Future Journal of Pharmaceutical Sciences, 2021 - Springer
Background Influenza is an acute respiratory tract infection caused by the influenza virus.
Vaccination and antiviral drugs are the two methods opted to control the disease. Besides …
Vaccination and antiviral drugs are the two methods opted to control the disease. Besides …
Optimal combination of anti-inflammatory components from Chinese medicinal formula Liang-Ge-San
Z Lu, H Cao, D Liu, Y Zheng, C Tian, S Liu… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Liang-Ge-San (LGS), a traditional Chinese
medicine (TCM) formula, is usually used in acute inflammatory diseases in China. Aim of the …
medicine (TCM) formula, is usually used in acute inflammatory diseases in China. Aim of the …
Network-Based Identification and Experimental Validation of Drug Candidates Toward SARS-CoV-2 via Targeting Virus–Host Interactome
J Fang, Q Wu, F Ye, C Cai, L Xu, Y Gu, Q Wang… - Frontiers in …, 2021 - frontiersin.org
Despite that several therapeutic agents have exhibited promising prevention or treatment on
Coronavirus disease-2019 (COVID-19), there is no specific drug discovered for this …
Coronavirus disease-2019 (COVID-19), there is no specific drug discovered for this …
Cdc2-like kinases: structure, biological function, and therapeutic targets for diseases
M Song, L Pang, M Zhang, Y Qu, KV Laster… - Signal Transduction and …, 2023 - nature.com
Abstract The CLKs (Cdc2-like kinases) belong to the dual-specificity protein kinase family
and play crucial roles in regulating transcript splicing via the phosphorylation of SR proteins …
and play crucial roles in regulating transcript splicing via the phosphorylation of SR proteins …
[HTML][HTML] The CDK1 inhibitor, Ro-3306, is a potential antiviral candidate against influenza virus infection
L Zhao, Y Yan, Q Dai, Z Wang, J Yin, Y Xu, Z Wang… - Antiviral Research, 2022 - Elsevier
Many viruses use the host cell division cycle to facilitate replication. Cyclin-dependent
kinases (CDKs) are a group of serine/threonine kinases that play a central role in regulating …
kinases (CDKs) are a group of serine/threonine kinases that play a central role in regulating …