Tumor necrosis factor inhibitors as therapeutic agents for recurrent spontaneous abortion

H Wu, Q You, Y Jiang, F Mu - Molecular Medicine …, 2021 - spandidos-publications.com
Recurrent spontaneous abortion (RSA) is a troublesome pregnancy disorder that manifests
as sequential early pregnancy losses; its causes are diverse and complex. Among the …

Genetics of recurrent pregnancy loss among Iranian population

M Moghbeli - Molecular Genetics & Genomic Medicine, 2019 - Wiley Online Library
Background Recurrent pregnancy loss (RPL) is one of the most common reproductive
disorders which is defined as the occurrence of recurrent miscarriage before 24 weeks of …

TLR signaling pathway and the effects of main immune cells and epigenetics factors on the diagnosis and treatment of infertility and sterility

K Babaei, MA Nezhad, SNS Ziabari, E Mirzajani… - Heliyon, 2024 - cell.com
Recurrent pregnancy loss (RPL), often known as spontaneous miscarriages occurring two or
more times in a row, is a reproductive disease that affects certain couples. The cause of RPL …

Association between idiopathic recurrent pregnancy loss and genetic polymorphisms in cytokine and matrix metalloproteinase genes

U Wysocka, A Sakowicz, L Jakubowski… - Ginekologia …, 2021 - journals.viamedica.pl
Objectives: Recurrent reproductive loss (RPL) is a global health issue affecting a significant
number of women. Approximately half of miscarriages have an unexplained etiology …

Association between cytokine polymorphisms and recurrent pregnancy loss: A review of current evidence

S Stavros, P Panagopoulos… - … of Gynecology & …, 2024 - Wiley Online Library
Cytokines are a type of protein that play an important role in the immune response and can
also affect many physiological processes in the body. Cytokine polymorphisms refer to …

Role of tumor necrosis factor‐alpha‐238 G> A promoter region polymorphism on recurrent miscarriage: An association study and meta‐analysis

N Sudhir, M Kaur, S Singh, A Beri… - American Journal of …, 2023 - Wiley Online Library
Background Recurrent miscarriage (RM) is defined as the loss of two or more consecutive
pregnancies. A functional SNP,‐238G> A in the promoter region of TNF‐α, affects the gene …

[HTML][HTML] Understanding the potential immunogenetic role of TNFα-308 polymorphism in the pathogenesis of recurrent miscarriage

S Ali, S Majid, MN Ali, MZ Banday, S Taing - Heliyon, 2023 - cell.com
Background Recurrent miscarriage (RM) represents the spontaneous termination of two or
more successive pregnancies. TNFα is a proinflammatory cytokine that is often considered …

Investigating the role of EGF-CFC gene family in recurrent pregnancy loss through bioinformatics and molecular approaches

JM Bremm, JA Boquett, M Silva Michels… - Systems Biology in …, 2021 - Taylor & Francis
Recurrent pregnancy loss (RPL) is the most common reproductive failure, reaching 1-5% of
women throughout their lives, and having unknown etiology in 50% of the cases. In humans …

[PDF][PDF] Prevalence of TNFa (G308A and G238A) and LTa (A252G) polymorphisms in women with pregnancy loss‒study carried out in a private clinic of Mexico City

LIJ Estuardo, DM Carlos, AR Daniela - Obstet Gynecol Int J, 2021 - researchgate.net
Background The Tumor Necrosis Factor (TNF) is a cytokine first identified in sera of mice
treated with lipopolysaccharides as a mediator of tumor necrosis by inducing hemorrhagic …

Relación entre el polimorfismo g-238a del factor de necrosis tumoral alfa y la pérdida gestacional recurrente

RG Campos, AR Cabral, MCR Martínez… - … y obstetricia de …, 2024 - medigraphic.com
Objetivo: Determinar si existe asociación entre los polimorfismos G-308A (rs1800629) y G-
238A (rs361525) del promotor del factor de necrosis tumoral alfa y la pérdida gestacional …