Background Multimorbidity, the coexistence of multiple health conditions, is a growing public
health challenge. Research and intervention development are hampered by the lack of …

The concept of multimorbidity has attracted growing interest over recent years, and more
latterly with the publication of specific guidelines on multimorbidity by the National Institute …

The immune system is the central regulator of tissue homeostasis, ensuring tissue
regeneration and protection against both pathogens and the neoformation of cancer cells. Its …

Background One of the major threats looming over the growing older population is frailty. It is
a distinctive health state characterised by increased vulnerability to internal and external …

While both terms focus on the occurrence of multiple chronic conditions within the same
individual, the term “comorbidity” refers to the combined effects of additional conditions in …

Background Frailty predicts poorer outcomes and decreased anticoagulation use in patients
with nonvalvular atrial fibrillation. We sought to assess the effectiveness and safety of …

Introduction Older people experiencing homelessness (PEH) are a rapidly growing
population at risk of accelerated aging and the early onset of geriatric conditions. One …

Background Patients with atrial fibrillation (AF) and frailty are a considerable group in clinical
practice. However, existing studies provide insufficient evidence of anticoagulation …

Background: Frail patients with atrial fibrillation (AF) are less likely to receive anticoagulation
than nonfrail patients with AF despite frailty being associated with poorer clinical outcomes …

Path analysis allows for an understanding of the complex interrelationships between
multiple variables and interactions in the octogenarians. The aim of this study was to …