Significant advances have been made in the past 20 years in the treatment and support of
children with cancer. Nutritional staging, assessment, and support are now recognized as …

One hundred and fifteen previously untreated adults aged over 60 years were referred to St
Bartholomew's Hospital between 1978 and 1986 for management of acute myeloid …

Twenty-six patients with acute leukaemia and 14 with high-grade lymphoma received
cytosine arabinoside (ara-C) at a twice daily dose of 2 g/m 2 administered as a 3-h infusion …

Since 1978, 187 patients (age range, 15 to 59, median 44 years) have received short-term
chemotherapy as part of three sequential open studies (B-IX, X, Xb) or a randomized clinical …

The cell cycle perturbation effect on leukemic cells of the Brown Norway myelocytic
leukemia (BNML) after high dose Ara-C injection was used as the rationale for …

It is widely held that major progress has been made during the past decade in the medical
management of acute nonlymphocytic leukemia (ANLL) and that with the regimens of the …

A series of 46 patients with acute leukaemia were treated with amsacrine (m-AMSA) and
cytosine arabinoside (ara-C). Complete remission (CR) was achieved in 15 of 38 (40%) …

Twenty-seven adults with refractory or recurrent acute leukaemia were treated with cytosine
arabinoside (ara-C) 2 g/m 2 infused over 3 h, every 12 h for 6 days, either alone (regimen A) …

Publisher Summary This chapter deals with the implications of use of cytostatics and
immunosuppressive drugs. The cardiotoxic effects of cytostatics should be borne in mind …

Combination chemotherapy programmes that include cytosine arabinoside and an
anthracycline antibiotic can cure adult patients with acute nonlymphoblastic leukaemia [1] …