Significance of chalcone scaffolds in medicinal chemistry

R Mazumder, Ichudaule, A Ghosh, S Deb… - Topics in Current …, 2024 - Springer
Chalcone is a simple naturally occurring α, β-unsaturated ketone with biological importance,
which can also be easily synthesized in laboratories by reaction between two aromatic …

Pharmacokinetic correlation of structurally modified chalcone derivatives as promising leads to treat tuberculosis

S Sabarathinam, N Ganamurali… - Future Medicinal …, 2023 - Taylor & Francis
In this study, we evaluated the potential of curated structurally modified chalcone derivatives
as anti-tuberculosis (TB) agents through computer-aided drug design. Compounds from the …

Synthesis of Bis-Chalcones and Evaluation of Its Effect on Peroxide-Induced Cell Death and Lipopolysaccharide-Induced Cytokine Production

A Tom, J Jacob, M Mathews, R Rajagopal, A Alfarhan… - Molecules, 2023 - mdpi.com
Plant secondary metabolites are important sources of biologically active compounds with
wide pharmacological potentials. Among the different classes, the chalcones form integral …

The Synthesis of 2′-Hydroxychalcones under Ball Mill Conditions and Their Biological Activities

I Abid, W Moslah, S Cojean, N Imbert, PM Loiseau… - Molecules, 2024 - mdpi.com
Chalcones are polyphenols that belong to the flavonoids family, known for their broad
pharmacological properties. They have thus attracted the attention of chemists for their …

Antioxidant, hepatoprotective & nephroprotective potential of a novel synthetic compound 2′, 3′-dihydroxybenzylidene in paracetamol intoxicated rats

M Attaullah, A Ullah, M Hussain, M Zahoor, R Ullah… - Heliyon, 2023 - cell.com
Paracetamol is a commonly used analgesic and antipyretic drug, but at a high dose level, it
leads to deleterious side effects. The need to investigate new hepatoprotective drugs is …

A concise review on synthesis, anti-inflammatory and antioxidant activities of chalcone

D Singh, V Kaundal, N Aggarwal… - Asian Journal of …, 2022 - indianjournals.com
Chalcones and their derivatives have been an area of great interest in recent years.
Numbers of research publications have been published and chalcones continue to show …

A Laconic Review on Chalcones: Synthesis, Antimicrobial and Antioxidant activities

V Kaundal, D Singh, A Devi, S Jindal, AD Ankalgi… - 2022 - indianjournals.com
Chalcones and their derivatives have been an area of great interest for several researchers
in recent years. Several number of research publications have been published and …

Ameliorative Potentials of Persea americana Mill (Avocado) Seed Extract on Acetaminophen-induced Hepatic Insufficiency in Rats

EA Ogbonnaya, DC Belonwu… - Asian Journal of …, 2024 - research.sdpublishers.net
Aim: The ability of ethylacetate extract of Persea americana Mill (avocado) seed to
ameliorate the hepatotoxic effect of acetaminophen in rats was assessed. Methodology …

[HTML][HTML] A Laconic Review on Chalcones: Synthesis, Antimicrobial and Antioxidant activities

AD Ankalgi, K Goyal - ajpsonline.com
Chalcones and their derivatives have been an area of great interest for several researchers
in recent years. Several number of research publications have been published and …