Pharmacology, physiology and genetics of the neuropeptide s system

RK Reinscheid, C Ruzza - Pharmaceuticals, 2021 - mdpi.com
The Neuropeptide S (NPS) system is a rather 'young'transmitter system that was discovered
and functionally described less than 20 years ago. This review highlights the progress that …

Human-specific neuropeptide S receptor variants regulate fear extinction in the basal amygdala of male and female mice depending on threat salience

X Bengoetxea, L Goedecke, J Remmes, P Blaesse… - Biological …, 2021 - Elsevier
Background A nonsynonymous single nucleotide polymorphism in the neuropeptide S
receptor 1 (NPSR1) gene (rs324981) results in isoleucine-to-asparagine substitution at …

Neandertal introgression and accumulation of hypomorphic mutations in the neuropeptide S (NPS) system promote attenuated functionality

RK Reinscheid, F Mafessoni, A Lüttjohann, K Jüngling… - Peptides, 2021 - Elsevier
The neuropeptide S (NPS) system plays an important role in fear and fear memory
processing but has also been associated with allergic and inflammatory diseases. Genes for …

Neuropeptide S (NPS) variants modify the signaling and risk effects of NPS Receptor 1 (NPSR1) variants in asthma

N Acevedo, S Ezer, S Kebede Merid, VD Gaertner… - PLoS …, 2017 - journals.plos.org
Single nucleotide polymorphisms (SNPs) close to the gain-of-function substitution, Asn (107)
Ile (rs324981, A> T), in Neuropeptide S Receptor 1 (NPSR1) have been associated with …

[HTML][HTML] Neuropeptide S encodes stimulus salience in the paraventricular thalamus

C Garau, X Liu, S Schulz, RK Reinscheid - Neuroscience, 2022 - Elsevier
Abstract Evaluation of stimulus salience is critical for any higher organism, as it allows for
prioritizing of vital information, preparation of responses, and formation of valuable memory …

Structural variation between neuropeptide isoforms affects function in the lobster cardiac system

AJ Muscato, DJ Powell, W Bulhan… - General and …, 2022 - Elsevier
Neuronal responses to peptide signaling are determined by the specific binding of a peptide
to its receptor (s). For example, isoforms of the same peptide family can drive distinct …

Neuropeptide S receptor gene Asn107 polymorphism in obese male individuals in Pakistan

A Ahmad, F Almsned, P Ghazal, MW Ahmed, MS Jafri… - Plos one, 2020 - journals.plos.org
Neuropeptide S (NPS) is a naturally occurring appetite stimulant, associated with anxiety,
stress, and excitement regulation. Neuropeptide S serves as a hypothalamic energy …

Mechanisms underlying variable responses to the neuropeptide C-type allatostatin (AST-C) across isoforms and among individuals in the American lobster, Homarus …

AJ Muscato - 2020 - digitalcommons.bowdoin.edu
Central pattern generators (CPGs) produce patterned outputs independent of sensory input.
The cardiac neuromuscular system of the American lobster (Homarus americanus) is driven …

[PDF][PDF] СОВРЕМЕННЫЕ ОСОБЕННОСТИ ПАТОГЕНЕЗА БРОНХИАЛЬНОЙ АСТМЫ И ВКЛАД МИКРОЦИРКУЛЯЦИИ В РАЗВИТИЕ ХРОНИЧЕСКОЙ …

ПВ Бережанский… - … », 27-28 МАРТА 2018 г …, 2018 - fulltext.kurskmed.com
Представлен детальный анализ современных данных, касающихся нарушений
системы микроциркуляции и гемореологии при аллергических заболеваниях …