Oligodendrocyte lineage cells and depression

B Zhou, Z Zhu, BR Ransom, X Tong - Molecular psychiatry, 2021 - nature.com
Depression is a common mental illness, affecting more than 300 million people worldwide.
Decades of investigation have yielded symptomatic therapies for this disabling condition but …

An inflammation-centric view of neurological disease: beyond the neuron

SD Skaper, L Facci, M Zusso, P Giusti - Frontiers in cellular …, 2018 - frontiersin.org
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …

Social isolation and the brain: effects and mechanisms

Y Xiong, H Hong, C Liu, YQ Zhang - Molecular psychiatry, 2023 - nature.com
An obvious consequence of the coronavirus disease (COVID-19) pandemic is the worldwide
reduction in social interaction, which is associated with many adverse effects on health in …

[HTML][HTML] Cannabidiol reduces airway inflammation and fibrosis in experimental allergic asthma

F Vuolo, SC Abreu, M Michels, DG Xisto… - European journal of …, 2019 - Elsevier
Asthma is characterized by chronic lung inflammation and airway hyperresponsiveness.
Asthma remains a major public health problem and, at present, there are no effective …

Regional gray matter oligodendrocyte-and myelin-related measures are associated with differential susceptibility to stress-induced behavior in rats and humans

KLP Long, LL Chao, Y Kazama, A An, KY Hu… - Translational …, 2021 - nature.com
Individual reactions to traumatic stress vary dramatically, yet the biological basis of this
variation remains poorly understood. Recent studies demonstrate the surprising plasticity of …

Physiology of oligodendroglia

AM Butt, M Papanikolaou, A Rivera - Neuroglia in Neurodegenerative …, 2019 - Springer
Oligodendrocytes are the myelinating cells of the CNS, producing the insulating myelin
sheath that facilitates rapid electrical conduction of axonal action potentials …

The endocannabinoid system and oligodendrocytes in health and disease

AA Ilyasov, CE Milligan, EP Pharr… - Frontiers in …, 2018 - frontiersin.org
Cannabinoid-based interventions are being explored for central nervous system (CNS)
pathologies such as neurodegeneration, demyelination, epilepsy, stroke, and trauma. As …

Neurodevelopmental toxicity assessment of flame retardants using a human DNT in vitro testing battery

J Klose, M Pahl, K Bartmann, F Bendt, J Blum… - Cell biology and …, 2021 - Springer
Due to their neurodevelopmental toxicity, flame retardants (FRs) like polybrominated
diphenyl ethers are banned from the market and replaced by alternative FRs, like …

Gabapentin—Friend or foe?

M Russo, B Graham, DM Santarelli - Pain Practice, 2023 - Wiley Online Library
Background Gabapentin is a recommended first‐line agent for treating neuropathic pain;
however, its efficacy rate is reportedly low, and the risk of adverse events is high. A plausible …

Glial cell AMPA receptors in nervous system health, injury and disease

M Ceprian, D Fulton - International journal of molecular sciences, 2019 - mdpi.com
Glia form a central component of the nervous system whose varied activities sustain an
environment that is optimised for healthy development and neuronal function. Alpha-amino …