The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …

Vascular nitric oxide (NO•) resistance, manifested by an impaired vasodilator function of NO•
in both the macro-and microvessels, is a common state in type 2 diabetes (T2D) associated …

Arginase is a ubiquitous enzyme in the urea cycle (UC) that hydrolyzes L‐arginine to urea
and L‐ornithine. Two mammalian arginase isoforms, arginase1 (ARG1) and arginase2 …

Abstract Purpose of Review Watermelon (Citrullus lanatus) distinctively contains l-citrulline
and l-arginine, precursors of nitric oxide (NO), along with polyphenols and carotenoids …

Type 2 diabetes mellitus (T2DM) is becoming a major contributor to cardiovascular disease.
One of the early signs of T2DM associated cardiovascular events is the development of …

This study is an attempt to find whether arginine metabolism dysregulation by arginase
activity is related to hyperglycemia, followed by changes in nitric oxide (NO) generation in …

Genetic polymorphisms mapped in the ARG1 locus (chr6: 131894344-131905472) and their
functional effects on type 2 diabetes mellitus (T2DM) have not been thoroughly elucidated to …

Arginase was purified from human serum of healthy and patient with type II Diabetes mellitus
subjects. The purification steps included, DEAE-cellulose chromatography and gel filtration …

Background: Arginase plays an essential role in type 2 diabetes. Aim of the study: The study
aimed to determine the level of arginase activity in individuals patients with diabetes mellitus …

Excessive soluble fms-like tyrosine kinase-1 (sFlt-1) has been strongly implicated in
preeclampsia. An increase in the serum sFlt-1 level occurs before the onset of preeclampsia …