Current state of play for HPV-positive oropharyngeal cancers

F Deutsch, IR Bullen, K Nguyen, NH Tran… - Cancer Treatment …, 2022 - Elsevier
Abstracte Clinically, HPV-positive oropharyngeal cancers (OPCs) have been shown to have
a distinct prognosis, compared to HPV-negative tumours, particularly in survival rates and …

Relevance of human papillomaviruses in head and neck cancer—what remains in 2021 from a clinician's point of view?

M Hoffmann, ES Quabius - Viruses, 2021 - mdpi.com
Human papillomaviruses (HPV) cause a subset of head and neck cancers (HNSCC). HPV16
predominantly signs responsible for approximately 10% of all HNSCC and over 50% of …

Return to work and self-reported swallowing following transoral robotic surgery for early-stage oropharyngeal squamous cell carcinoma: A retrospective cohort study

P Staibano, M Au, M Xie, MK Gupta, JEMT Young… - Oral Oncology, 2024 - Elsevier
Background Treatment de-intensification, including transoral robotic surgery (TORS), may
outcomes in HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). Early return …

Identification of high-risk human papillomavirus DNA, p16, and E6/E7 oncoproteins in laryngeal and hypopharyngeal squamous cell carcinomas

A Lifsics, V Groma, M Cistjakovs, S Skuja, R Deksnis… - Viruses, 2021 - mdpi.com
Human papillomavirus (HPV) was proven to play a significant role in cancer development in
the oropharynx. However, its role in the development of laryngeal (LSCC) and …

PSMC2, ORC5 and KRTDAP are specific biomarkers for HPV‑negative head and neck squamous cell carcinoma

Y Su, Z Zeng, D Rong, Y Yang, B Wu… - Oncology …, 2021 - spandidos-publications.com
The prognosis of patients with human papillomavirus (HPV)‑negative head and neck
squamous cell carcinoma (HNSCC) is poorer than those with HPV‑positive HNSCC. The …

High-Risk HPV CISH Detection in Cervical Biopsies with Weak and/or Focal p16 Immunohistochemical Positivity

D Cabibi, AG Giannone, A Quattrocchi… - International Journal of …, 2024 - mdpi.com
In cervical biopsies, for diagnosis of Human Papilloma Virus (HPV) related conditions, the
immunohistochemical staining for p16 has a diagnostic value only if diffusely and strongly …

Tumour infiltrating lymphocytes in oropharyngeal carcinoma: Prognostic value and evaluation of a standardised method

SJ De Keukeleire, T Vermassen, A De Meulenaere… - Pathology, 2021 - Elsevier
Tumour infiltrating lymphocytes (TILs) have been described as a biomarker for the host
immune response against the tumour with prognostic properties. The International Immuno …

Diabetes can increase the prevalence of EBV infection and worsen the prognosis of nasopharyngeal carcinoma

S Midorikawa, H Mizukami, K Kudoh, Y Takeuchi… - Pathology, 2024 - Elsevier
Epstein‒Barr virus (EBV) infection is a primary oncogenic factor of nasopharyngeal
carcinoma (NPC) that elicits epithelial–mesenchymal transition (EMT). Although diabetic …

Tumor cell extrinsic synaptogyrin 3 expression as a diagnostic and prognostic biomarker in head and neck cancer

RM Murphy, J Tasoulas, A Porrello, MB Carper… - Cancer research …, 2022 - AACR
Over 70% of oropharyngeal head and neck squamous cell carcinoma (HNSC) cases in the
United States are positive for human papillomavirus (HPV) yet biomarkers for stratifying …

Molecular and clinical aspects of oropharyngeal squamous cell carcinoma associated with human Papillomavirus

DS Polatova, AY Madaminov - Head and Neck Tumors (HNT), 2021 - ogsh.abvpress.ru
Currently, the role of human papillomavirus (HPV) in carcinogenesis is well known: more
than 90% of HPV-positive oropharyngeal squamous cell carcinomas are caused by HPV …