The discovery of the first “living” radical polymerization by Otsu and co-workers (1) in 1982
heralded the start of a very exciting time for polymer chemists. Since then, a plethora of living …

Polysaccharide-based microgels/nanogels have high water content, functionality,
biocompatibility, tunable size from submicrons to tens of nanometers, large surface area for …

Interest in the development of new hybrid materials based on natural polysaccharides has
grown exponentially in the last decade. Such materials are commonly obtained by the graft …

This review covers the literature concerning the modification of polysaccharides through
controlled radical polymerizations (NMP, ATRP and RAFT). The different routes to well …

Pullulan due to its specificity for liver has been widely exploited for biomedical applications.
In this work, a tailor-made biocleavable pullulan-based gene vector (PuPGEA) with good …

Inclusion of various polymeric chains with different lengths and functionalities (such as
hydrophobic, ionic, acidic, basic, etc) into polysaccharide backbones leads to new polymeric …

It is an unquestionable fact that cancer, also called malignancy, has or will soon become the
major global health care problem with an increasing incidence worldwide. Conventional …

It is of crucial importance to modify dextran-based polysaccharides in the design of novel
biomedical materials. A simple one-step method, involving the reaction of hydroxyl groups of …

Natural saccharides are involved in numerous biological processes. It has been shown that
these carbohydrates play a role in cell adhesion and proliferation, as well as protein …

It is of crucial importance to design reduction-sensitive polysaccharide-based copolymers for
intracellular triggered gene and drug delivery. In this work, a simple two-step method …