Implants with sensing capabilities

M Veletic, EH Apu, M Simic, J Bergsland… - Chemical …, 2022 - ACS Publications
Because of the aging human population and increased numbers of surgical procedures
being performed, there is a growing number of biomedical devices being implanted each …

Wearable EEG and beyond

AJ Casson - Biomedical engineering letters, 2019 - Springer
The electroencephalogram (EEG) is a widely used non-invasive method for monitoring the
brain. It is based upon placing conductive electrodes on the scalp which measure the small …

Chronic adaptive deep brain stimulation versus conventional stimulation in Parkinson's disease: a blinded randomized feasibility trial

CR Oehrn, S Cernera, LH Hammer, M Shcherbakova… - Nature Medicine, 2024 - nature.com
Deep brain stimulation (DBS) is a widely used therapy for Parkinson's disease (PD) but
lacks dynamic responsiveness to changing clinical and neural states. Feedback control …

First-in-human prediction of chronic pain state using intracranial neural biomarkers

P Shirvalkar, J Prosky, G Chin, P Ahmadipour… - Nature …, 2023 - nature.com
Chronic pain syndromes are often refractory to treatment and cause substantial suffering
and disability. Pain severity is often measured through subjective report, while objective …

A wireless millimetre-scale implantable neural stimulator with ultrasonically powered bidirectional communication

DK Piech, BC Johnson, K Shen, MM Ghanbari… - Nature biomedical …, 2020 - nature.com
Clinically approved neural stimulators are limited by battery requirements, as well as by their
large size compared with the stimulation targets. Here, we describe a wireless, leadless and …

The modulatory effect of adaptive deep brain stimulation on beta bursts in Parkinson's disease

G Tinkhauser, A Pogosyan, S Little, M Beudel, DM Herz… - Brain, 2017 - academic.oup.com
Adaptive deep brain stimulation uses feedback about the state of neural circuits to control
stimulation rather than delivering fixed stimulation all the time, as currently performed. In …

A wireless and artefact-free 128-channel neuromodulation device for closed-loop stimulation and recording in non-human primates

A Zhou, SR Santacruz, BC Johnson… - Nature biomedical …, 2019 - nature.com
Closed-loop neuromodulation systems aim to treat a variety of neurological conditions by
delivering and adjusting therapeutic electrical stimulation in response to a patient's neural …

Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor

E Opri, S Cernera, R Molina, RS Eisinger… - Science translational …, 2020 - science.org
Deep brain stimulation (DBS) is an approved therapy for the treatment of medically refractory
and severe movement disorders. However, most existing neurostimulators can only apply …

A mm-sized wireless implantable device for electrical stimulation of peripheral nerves

J Charthad, TC Chang, Z Liu, A Sawaby… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
A wireless electrical stimulation implant for peripheral nerves, achieving> 10× improvement
over state of the art in the depth/volume figure of merit, is presented. The fully integrated …

Device profile of the percept PC deep brain stimulation system for the treatment of Parkinson's disease and related disorders

J Jimenez-Shahed - Expert Review of Medical Devices, 2021 - Taylor & Francis
Introduction: Several software and hardware advances in the field of deep brain stimulation
(DBS) have been realized in recent years and devices from three manufacturers are …