Nanomedicines based drug delivery systems for anti-cancer targeting and treatment

V Jain, S Jain, SC Mahajan - Current drug delivery, 2015 - ingentaconnect.com
Cancer is defined as an uncontrolled growth of abnormal cells. Current treatment strategies
for cancer include combination of radiation, chemotherapy and surgery. The long-term use …

An in vitro evaluation of antitumor activity of sirolimus-encapsulated liposomes in breast cancer cells

U Nandi, I Onyesom, D Douroumis - Journal of Pharmacy and …, 2021 - academic.oup.com
Objectives Design and examine the effect of sirolimus-PEGylated (Stealth) liposomes for
breast cancer treatment. In this study, we developed conventional and Stealth liposome …

Encapsulation into Stealth Liposomes Enhances the Antitumor Action of Recombinant Cratylia mollis Lectin Expressed in Escherichia coli

CRA Cunha, LCN Silva, FJF Almeida… - Frontiers in …, 2016 - frontiersin.org
This study evaluated the in vivo antitumor potential of the recombinant lectin from seeds of
Cratylia mollis (rCramoll) expressed in Escherichia coli, free or encapsulated in stealth …

In vivo evaluation of the anticancer activity of the gemcitabine and doxorubicin combined in a nanoemulsion

MH Alkhatib, WS Alshehri, FB Abdu - Journal of Pharmacy and …, 2018 - journals.lww.com
Aim: To detect the antitumor activity of the combination formulas of GEM and DOX, loaded
either in water (GEM+ DOX-Sol) or in NEs (GEM–DOX combination/loaded NE [GEM+ …

Cytotoxic effect of the combination of gemcitabine and atorvastatin loaded in nanoparticle on the MCF-7 breast cancer cells and HFS human foreskin cells

MH Alkhatib, DA Al-Saedi - Current nanoscience, 2017 - ingentaconnect.com
Background: The combination of anticancer drugs in nanoparticles has great potential as a
promising strategy to maximize drug efficacies. Gemcitabine (GEM), a nucleoside analogue …

Biodistribution study of 99mTc-gemcitabine-loaded spherulites in Sprague–Dawley rats by gamma scintigraphy to investigate its lung targeting potential

R Dhande, A Tyagi, RK Sharma… - Journal of …, 2017 - Taylor & Francis
Gemcitabine hydrochloride (GCH) is drug of choice for treatment of non-small cell lung
cancer. This project aims to formulate GCH-loaded spherulites for lung targeting using …

Formulation characterization and stability study of encapsulated anticancer drug in multilayered PEGylated tumor targeting stealth liposomes

M Padmasree - 2022 - search.proquest.com
Introduction: Cancer is one of the major causes of death worldwide. Cancer can be treated
with surgery, radiation, and chemotherapy, but these often result in infections or numerous …

Combination therapy of lamivudine and zidovudine using sterically stabilized liposomes: development and characterization

V Gavini - Asian Journal of Pharmaceutics (AJP), 2016 - asiapharmaceutics.info
Aim: Lamivudine and zidovudine are nucleoside reverse-transcriptase inhibitors with activity
against human immunodeficiency virus type 1 (HIV-1). However, only temporary and limited …

[PDF][PDF] Enhanced Tumor Targeting and Antitumor Activity of Gemcitabine Encapsulated Stealth Liposome's

GS Bangale, R Kesarala, GV Shinde - INDIAN JOURNAL OF …, 2015 - ijper.org
Introduction: Cancer is a term used for diseases in which abnormal cells divide without
control and are able to invade other tissues. Gemcitabine is new cytotoxic drug but some of …

Design, development and characterization of solid lipid nanoparticles of gemcitabine hydrochloride

AS Mokashi, NR Jadhav, SB Rooge - Drug Delivery Letters, 2012 - ingentaconnect.com
Gemcitabine hydrochloride (Gem HCL) is a drug of choice for the treatment of most cancers,
as a single or in combination chemotherapy. However, its bioavailability is a major concern …