The use of complementary medicine has recently increased in an attempt to find effective
alternative therapies that reduce the adverse effects of drugs. Punica granatum …

Understanding mechanism of neuropathic pain is too complex and involves both peripheral
and central pathophysiological phenomenon. Accordingly the treatment of neuropathic pain …

Purpose.: Stimulation to the cornea via noxious chemical and mechanical means evokes
tearing, blinking, and pain. In contrast, mild cooling of the ocular surface has been reported …

Clinical studies suggest that essential oil of Eugenia caryophyllata (Clove) buds (EOEC) is
efficacious in the treatment of dental pain. In the present study, we investigated the …

It seems that histamine release in the site of neuronal injury could contribute to the
neuropathic pain mechanism. In the present study, we investigated the anti-allodynic effects …

The present study explored the interaction between histaminergic and opioidergic systems
at the level of the hippocampus in modulation of orofacial pain by intra-hippocampal …

Objective Temporomandibular disorders (TMD) are a group of conditions affecting the jaw,
surrounding muscles and associated structures. Researches indicate that TMD has …

Background The present study was aimed to investigate the effects of microinjection of
histamine and its H 1, H 2 and H 3 receptor antagonists, mepyramine, ranitidine and …

Brain neuronal histamine, through its receptors, is involved in central pain perception. In the
present study, the effect of microinjection of histamine, mepyramine (a histamine H1 receptor …

Objectives The present study examined the mechanisms involved in the antinociceptive
effects of bis selenide [(Z)-2, 3-bis (4-chlorophenylselanyl) prop-2-en-1-ol]. Methods The …