The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

Turmeric is traditionally used as a spice and coloring in foods. It is an important ingredient in
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …

In this work, chitosan/lignosulfonate composite micelles (CS-LS) were successfully prepared
through polyelectrolyte self-assembly. Curcumin was encapsulated in CS-LS to obtain CUR …

BACKGROUND. Noninvasive detection of Alzheimer's disease (AD) with high specificity and
sensitivity can greatly facilitate identification of at-risk populations for earlier, more effective …

Alzheimer's disease (AD) is one of the most common neurodegenerative disorders, with no
cure and preventive therapy. Misfolding and extracellular aggregation of Amyloid-β (Aβ) …

Curcumin, a polyphenolic natural product, exhibits therapeutic activity against a number of
diseases, attributed mainly to its chemical structure and unique physical, chemical, and …

In this article, we first designed and synthesized curcumin-based near-infrared (NIR)
fluorescence imaging probes for detecting both soluble and insoluble amyloid beta (Aβ) …

The natural product curcumin has gained considerable attention in recent years for its
multiple pharmacological activities, but more efforts are needed to understand how curcumin …

Amyloid aggregation is a hallmark of several degenerative diseases affecting the brain or
peripheral tissues, whose intermediates (oligomers, protofibrils) and final mature fibrils …

The aggregation of the 42-residue amyloid β-protein (Aβ42) is involved in the pathogenesis
of Alzheimer disease (AD). Numerous flavonoids exhibit inhibitory activity against Aβ42 …