[HTML][HTML] An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles

M Baumann, IR Baxendale - Beilstein journal of organic …, 2013 - beilstein-journals.org
This review which is the second in this series summarises the most common synthetic routes
as applied to the preparation of many modern pharmaceutical compounds categorised as …

Developments in the chemistry of 2-pyridone

WS Hamama, M Waly, I El-Hawary… - Synthetic …, 2014 - Taylor & Francis
Full article: Developments in the Chemistry of 2-Pyridone Skip to Main Content Taylor and
Francis Online homepage Taylor and Francis Online homepage Log in | Register Cart 1.Home …

Synthesis, physicochemical and vibrational spectral properties of 2–pyridone and 2–aminopyridine derivatives: An experimental and theoretical study

RM Keshk, M Garavelli, MMT El–Tahawy - Journal of Molecular Structure, 2021 - Elsevier
A convenient and efficient one–pot three–component reaction of acetyl acetone,
malononitrile and ammonium acetate was investigated for the synthesis of 3–cyano–4, 6 …

Preparation of Azinones from (Cyclopropylmethoxy) azine Ethers

AT Londregan, JM Curto, E Hastry… - The Journal of …, 2023 - ACS Publications
A general and convenient procedure for the synthesis of azinones is presented.
Cyclopropylmethanol is readily introduced onto various azines where it functions as both a …

Synthesis and luminescent properties and theoretical investigation on electronic structure of nitrile-based 2-pyridone molecules

L Chen, X Liu, B Xu, C Sun, P Tao - Spectrochimica Acta Part A: Molecular …, 2011 - Elsevier
3-Cyano-4, 6-dimethyl-2-pyridone and 3-cyano-4-methyl-6-phenyl-2-pyridone were
synthesized effectively by the reaction of readily available 1, 3-diketone and malononitrile …

[PDF][PDF] Crystal structure of 4-(naphthalen-2-yl)-2-oxo-6-phenyl-1, 2-dihydropyridine-3-carbonitrile

TTT Bui, DH Mac, P Quang Trung… - Acta Crystallographica …, 2023 - journals.iucr.org
The synthesis and crystal structure of the title compound, C22H14N2O, are described. The
title compound was synthesized by a three-component one-pot reaction in DMSO involving …

Theorectical Study of Tautomerism, Physicochemical and ADMET Properties of 2-Pyridone Derivatives

N Sadallah, IE Charif, H Chemouri - Theoretical Foundations of Chemical …, 2023 - Springer
Physicochemical and pharmacokinetic properties represent the fundamental properties of
drugs and affect their bioavailability. In this work, these properties are calculated and used to …

Synthesis, X-ray and spectroscopic analysis of some pyridine derivatives

M Cetina, M Tranfić, I Sviben, M Jukić - Journal of molecular structure, 2010 - Elsevier
Three pyridine derivatives, 4-(methoxymethyl)-6-methyl-2-oxo-1, 2-dihydropyridine-3-
carbonitrile (1), 4-(methoxymethyl)-6-methyl-5-nitro-2-oxo-1, 2-dihydropyridine-3-carbonitrile …

N-(4-Bromophenacyl)-4, 6-dimethyl-2-oxo-1, 2-dihydropyridine-2-carbonitrile

DV Albov, EI Turubanova, VB Rybakov… - … Section E: Structure …, 2004 - scripts.iucr.org
organic papers Page 1 organic papers o1222 Dmitry V. Albov et al. C16H13BrN2O2 DOI:
10.1107/S1600536804014175 Acta Cryst. (2004). E60, o1222±o1223 Acta …

Transformations of Substituted Oxazolo- [3,2-a]Pyridines to 5,6-Disubstituted Indolizines: Synthesis And X-ray Structural Mapping

VB Rybakov, EV Babaev - Chemistry of Heterocyclic Compounds, 2014 - Springer
The treatment of 4, 6-dimethyl-2-oxonicotinic nitrile, amide, and ethyl ester with p-
bromophenacyl bromide produced N-alkyl isomers, which cyclized in the presence of …