Clinical effects of curcumin in enhancing cancer therapy: A systematic review

K Mansouri, S Rasoulpoor, A Daneshkhah, S Abolfathi… - BMC cancer, 2020 - Springer
Background Curcumin is herbal compound that has been shown to have anti-cancer effects
in pre-clinical and clinical studies. The anti-cancer effects of curcumin include inhibiting the …

Development of multifunctional molecules as potential therapeutic candidates for Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis in the …

MG Savelieff, G Nam, J Kang, HJ Lee, M Lee… - Chemical …, 2018 - ACS Publications
Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

Curcumin and health

M Pulido-Moran, J Moreno-Fernandez… - Molecules, 2016 - mdpi.com
Nowadays, there are some molecules that have shown over the years a high capacity to act
against relevant pathologies such as cardiovascular disease, neurodegenerative disorders …

Alpha-synuclein oligomers: a new hope

N Bengoa-Vergniory, RF Roberts, R Wade-Martins… - Acta …, 2017 - Springer
Alpha-synuclein is a protein implicated in Parkinson's disease and thought to be one of the
main pathological drivers in the disease, although it remains unclear how this protein elicits …

Nrf2–ARE pathway: an emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases

I Buendia, P Michalska, E Navarro, I Gameiro… - Pharmacology & …, 2016 - Elsevier
Neurodegenerative diseases (NDDs) are predicted to be the biggest health concern in this
century and the second leading cause of death by 2050. The main risk factor of these …

Oral bioavailability of curcumin: problems and advancements

W Liu, Y Zhai, X Heng, FY Che, W Chen… - Journal of drug …, 2016 - Taylor & Francis
Curcumin is a natural compound of Curcuma longa L. and has shown many
pharmacological activities such as anti-inflammatory, anti-oxidant in both preclinical and …

Protective effects of Indian spice curcumin against amyloid-β in Alzheimer's disease

PH Reddy, M Manczak, X Yin… - Journal of …, 2018 - content.iospress.com
The purpose of our article is to assess the current understanding of Indian spice, curcumin,
against amyloid-ß (Aß)-induced toxicity in Alzheimer's disease (AD) pathogenesis. Natural …

Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

J Nicolas, S Mura, D Brambilla, N Mackiewicz… - Chemical Society …, 2013 - pubs.rsc.org
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …

Natural product-based nanomedicine: recent advances and issues

R Watkins, L Wu, C Zhang, RM Davis… - International journal of …, 2015 - Taylor & Francis
Natural products have been used in medicine for many years. Many top-selling
pharmaceuticals are natural compounds or their derivatives. These plant-or microorganism …

Recent advancements in liposomes targeting strategies to cross blood-brain barrier (BBB) for the treatment of Alzheimer's disease

M Agrawal, DK Tripathi, S Saraf, S Saraf… - Journal of controlled …, 2017 - Elsevier
In this modern era, with the help of various advanced technologies, medical science has
overcome most of the health-related issues successfully. Though, some diseases still remain …