Copper is an essential nutrient whose redox properties make it both beneficial and toxic to
the cell. Recent progress in studying transition metal signalling has forged new links …

Copper is a vital mineral, and an optimal amount of copper is required to support normal
physiologic processes in various systems, including the cardiovascular system. Over the …

Conventional cancer therapies suffer from severe off-target effects because most of them
target critical facets of cells that are generally shared by all rapidly proliferating cells. The …

Cuproptosis is a novel type of copper-induced cell death that primarily occurs in cells that
utilize oxidative phosphorylation as the main metabolic pathway to produce energy. Copper …

Metal–organic frameworks (MOFs) are a class of important porous, crystalline materials
composed of metal ions (clusters) and organic ligands. Owing to the unique redox chemistry …

Copper (Cu) is a vital element required for cellular growth and development; however, even
slight changes in its homeostasis might lead to severe toxicity and deleterious medical …

Copper (Cu) homeostasis is gaining increasing attention in human health as both Cu
overload and deficiency evokes pathological changes including cardiovascular diseases …

Disulfiram (DSF) has been used as an alcoholism drug for 70 years. Recently, it has
attracted increasing attention owing to the distinguished anticancer activity, which can be …

Copper, an essential micronutrient, controls multiple fundamental processes throughout all
forms of life, such as respiration, cell proliferation and neurotransmitter biosynthesis. High …

Transition metal chemistry is essential to life, where metal binding to DNA, RNA, and
proteins underpins all facets of the central dogma of biology. In this context, metals in …