[HTML][HTML] Exploring Metabolic Mechanisms in Calcific Tendinopathy and Shoulder Arthrofibrosis: Insights and Therapeutic Implications

S Alam, MS Sargeant, R Patel, P Jayaram - Journal of Clinical Medicine, 2024 - mdpi.com
Rotator cuff calcific tendinopathy and arthrofibrosis of the shoulder (adhesive capsulitis) are
debilitating musculoskeletal disorders that significantly impact joint function and impair …

[HTML][HTML] Surface Molecular Markers for the Isolation of Viable Fibroblast Subpopulations in the Female Reproductive Tract: A Comprehensive Review

K Łuszczyński, M Komorowski, M Soszyńska… - International Journal of …, 2024 - mdpi.com
Advancements in single-cell analyzis technologies, particularly single-cell RNA sequencing
(scRNA-seq) and Fluorescence-Activated Cell Sorting (FACS), have enabled the analyzis of …

[HTML][HTML] PPP1R3A inhibits osteogenesis and negatively regulates intracellular calcium levels in calcific tendinopathy

C Hu, L Ma, S Gao, MY Yang, MD Mu, L Chang… - Iscience, 2023 - cell.com
Calcific tendinopathy (CT) is defined by the progressive accumulation of calcium crystals in
tendonic regions that results in severe pain in patients. The etiology of CT is not fully …

Are the mechanical properties of Achilles tendon altered in CrossFit athletes? Reliability and accuracy of myotonometry

S Szajkowski, J Pasek, M Dwornik… - Acta of Bioengineering …, 2023 - sciendo.com
Purpose: Tendons adapt to loads affecting them by changing tendons' mechanical and
morphological properties. The aim of the study was to investigate the influence of …

Human adipose stromal cells differentiate towards a tendon phenotype with extracellular matrix production and adapted visco-elastic properties in a 3D-culture system

M Horde, J Fouchard, X Laffray, C Blavet, V Bereziat… - bioRxiv, 2024 - biorxiv.org
Tendons are composed of type I collagen fibrils and specialized extracellular matrix (ECM)
proteins that are hierarchically organized to transmit forces from muscle to bone. Reliable …

Protective Association of Antihypertensive Drugs Against Tendinopathy Development Related to β-Adrenergic Signaling and L-Type Calcium Channel Function

H Li, CL Mendias, HA Awad, RJ Looney… - Scott A. and Ciufo … - papers.ssrn.com
Background: As current non-surgical standards of care for painful tendinopathy are
ineffective, developing non-operative, pharmacological interventions remain an unmet …

[PDF][PDF] Blocking CaV1. 2 function by verapamil mitigates tendinopathy and promotes scarless healing of injured Achilles tendon in mice

H Li, BF Boyce, C Cao - ors.org
Disclosures: The authors have nothing to disclose. Introduction: Tensile-bearing Achilles
tendons are highly prone to acute injury and chronic degeneration known as tendinopathy, a …

[PDF][PDF] Increased Ca2+ signaling through CaV1. 2 L-type voltage-gated Ca2+ channel regulates Achilles tendinopathy with heterotopic ossification formation

H Li, DJ Ciufo, BF Boyce, C Cao - ors.org
Methods: All animal studies were approved by the University Committee for Animal
Resources. Mice: This study used CaV1. 2+/lacZ reporter line, and two floxed CaV1. 2 …